血液灌流对急性有机磷中毒患者的救治疗效  

Effect of Hemoperfusion in the Treatment of Acute Severe Organophosphate Poisoning

作　　者：米崧[1] 曹志新[1] 李杰[1] 曹玉龙[1] 朱剑[1] 

机构地区：[1]首都医科大学附属北京朝阳医院 北京呼吸疾病研究所呼吸与危重症医学科

出　　处：《首都医科大学学报》2010年第5期657-659,共3页Journal of Capital Medical University

摘　　要：目的探讨血液灌流对急性重度有机磷中毒患者的疗效。方法选取2005年5月~2009年12月进行血液灌流的急性重度有机磷中毒患者31例,通过血液灌流治疗前后呼吸、循环状况、肝肾功能各项指标的对比,分析血液灌流治疗的临床效果。结果经血液灌流治疗后,患者肝肾功能、一般状况明显好转。31例患者中,18例气管插管患者,在血液灌流后12.5 h内顺利拔除气管内导管,成功撤机。11例患者在血液灌流前后进行血药浓度检测,血液灌流后明显低于治疗前（P〈0.05）。结论对于急性重度有机磷中毒患者,如存在神志异常,应尽早建立人工气道并早期进行血液灌流治疗,能有效改善患者的一般状况。Objective To evaluate the curative effect of hemoperfusion in the treatment of acute severe organophosphate poisoning.Methods 31 cases with acute severe organophosphate poisoning seen in our hospital from 2005 to 2009 were enrolled.The curative effect of hemoperfusion in the treatment was analyzed.Results After treatment,liver and kidney function,general condition improved markedly.18 cases received endotracheal intubation were successfully extubated.The blood poison level was determined before and after hemoperfusion.After treatment,the blood poison level was significantly lower than that before treatment（P0.05）.Conclusion If patients have abnormal consciousness,it is recommended that the artificial airway and early hemoperfusion should be performed as soon as possible,which can effectively improve the patient＇s general condition.

关 键 词：血液灌流 重度有机磷中毒 疗效 

分 类 号：R457.1[医药卫生—治疗学]