伴皮质下梗死和白质脑病常染色体显性遗传性脑动脉病CT平扫特点  

Features of CT plain scan in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

作　　者：杨运俊[1] 程敬亮[1] 陈伟建[2] 李建策[2] 金得辛[3] 

机构地区：[1]郑州大学第一附属医院放射科,郑州450052 [2]温州医学院附属第一医院放射影像中心,浙江325000 [3]温州医学院附属第一医院神经内科,浙江325000

出　　处：《放射学实践》2010年第10期1087-1089,共3页Radiologic Practice

摘　　要：目的:探讨伴皮质下梗死和白质脑病的常染色体显性遗传性脑动脉病(CADASIL)CT平扫特点。方法:对8例经临床、MRI、病理学及基因检查确诊为CADASIL患者的CT平扫资料进行回顾性分析。结果:CADASIL患者脑CT平扫特点主要表现为颞极、额叶前部白质疏松,可伴有腔隙性梗死灶,随年龄增长上述病灶逐渐加重。结论:CADASIL病例CT平扫存在特征性的脑白质病变,CT对该病的筛选有重要作用。Objective：To investigate the features in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy （CADASIL） by using CT plain scan.Methods：CT plain scan was performed in 8 patinets with CADASIL confirmed by clinics,MRI,pathology and genetical investigation,and the examination data were analyzed retrospectively.Results：CT plain scan revealed demyelination in white matter of temporal pole and frontal lobe with multiple lacular infarcts,which increased with the patient＇s age.Conclusion：CT plain scan is consistent with the pathological changes of white matter and plays a very important role in screening CADASIL cases.

关 键 词：脑梗死 脑血管病 体层摄影术 X线计算机 

分 类 号：R816.1[医药卫生—放射医学] R749.13[医药卫生—临床医学]