三维超声斑点追踪成像技术评价高血压患者左心室整体收缩功能的临床研究  

Clinical study of left ventricular global systolic function in patients with hypertension by three-dimensional ultrasound speckle tracking imaging

作　　者：李玉曼[1] 谢明星[1] 吕清[1] 付倩[1] 方凌云[1] 姜岚[1] 李蔚[1] 覃小娟[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院超声影像科湖北省分子影像重点实验室,武汉430022

出　　处：《中华超声影像学杂志》2010年第10期838-841,共4页Chinese Journal of Ultrasonography

摘　　要：目的 探讨三维超声斑点追踪成像技术评价原发性高血压患者左心室整体收缩功能的临床应用价值.方法 左室几何构型正常的原发性高血压患者50例,年龄、性别匹配的对照组29例.采取心尖全容积图像,应用三维超声斑点追踪成像技术测量并比较各组左室整体纵向收缩峰值应变（GLS）、左室整体径向收缩峰值应变（GRS）、左室整体圆周收缩峰值应变（GCS）及左室整体三维径向收缩峰值应变（3DGRS）,三维斑点追踪分析软件计算左室射血分数（LVEF）.结果 高血压患者左室GLS、GRS、GCS及3DGRS均较对照组减低,差异有统计学意义（P均＜0.05） Pearson相关分析表明高血压组左室GCS、GLS、GRS与LVEF相关（r1=0.930,P1＜0.001 r2=0.705,P2＜0.001 r3=0.474,P3=0.001）,对照组左室GCS、GLS与LVEF相关（r1=0.838,P1＜0.001 r2=0.697,P2＜0.001）.结论 高血压患者早期左室整体三维形变能力降低,三维超声斑点追踪成像技术可发现高血压患者早期心功能的变化.左室圆周运动在左室三维运动中占重要作用,对左室射血产生重要影响.Objective To assess left ventricular （LV） global systolic function in patients with essential hypertension with normal geometric LV by 3-dimensional ultrasound speckle tracking imaging（3D-STI）. Methods Fifty patients with essential hypertension were enrolled in this study, 29 normal subjects matched with age and sex were selected as control groups. LV global longitudinal peak systolic strain （GLS）, radial peak systolic strain （GRS）, circumferential peak systolic strain （GCS）, LV global 3-dimentional radial peak systolic strain （3DGRS） were measured in all subjects by 3D-STI from the apical full-volume image and compared between groups. LV ejection fraction （LVEF） was acquired from 3D-STI.Results Compared with controls, LV GLS, GRS, GCS and 3DGRS were significantly reduced in patients with hypertension （ P 〈 0.05 for all）. A Pearson correlate revealed that LV GCS, GLS and GRS corresponded with LVEF（ r1 =0.930, P1 〈0.001 r2 = 0.705, P2 〈0.001 r3 =0.474, P3 =0.001,respectively） in patients with hypertension, and LV GCS, GLS correlated with LVEF（ r1 = 0. 838, P1 〈0. 001 r2 = 0. 697, P2 〈 0. 001, respectively） in normal subjects. Conclusions LV global 3D strain decreases in patients with hypertension in the early period,3D-STI could evaluate the early change of heart function in patients with hypertension. LV circumferential movement plays a major role in the LV 3D movement and impacts on LVEF.

关 键 词：超声心动描记术 三维 高血压 心室功能 左 斑点追踪显像 

分 类 号：R686[医药卫生—骨科学]