超声造影时间-相对强度曲线在肝良恶性肿瘤鉴别诊断中的作用  

Time-relative-intensity curve of contrast-enhanced ultrasonography for discrimination of malignant and benign liver tumors

作　　者：赵玉珍[1] 孙昊鹏[1] 武敬平[1] 张丽娟[1] 臧树良[1] 祝晓东[1] 

机构地区：[1]卫生部中日友好医院超声科,北京100129

出　　处：《中华超声影像学杂志》2010年第10期870-873,共4页Chinese Journal of Ultrasonography

摘　　要：目的 探讨超声造影相对定量参数及时间-相对强度曲线（time-relative-intensity curve,TRIC）在肝良恶性肿瘤鉴别诊断中的价值.方法 对59枚肝局灶性病变行超声造影检查,绘制时间-强度曲线（time-intensity curve,TIC）,获取良恶性病灶的相对造影参数进行比较分析 将TIC中每帧图像病灶声强减去肝实质声强得到相对强度,以时间为横坐标,相对强度为纵坐标,绘制TRIC,对比良恶性病灶TRIC形态特征.结果 相对达峰时间、相对达峰强度、相对增强时间及相对下降斜率在良恶性组间差异有统计学意义（P＜0.05）,恶性病灶TRIC上升支及下降支均较陡直,在平均（28.24±8.14）s时达基线0值,并继续下降至基线下-8 dB附近小幅波动.良性病灶TRIC上升支及下降支均较平缓,且下降支下降至基线上4 dB附近小幅波动.结论 超声造影相对定量参数和TRIC为肝良恶性肿瘤的诊断提供了新的定量指标.Objective To study the diagnostic value of relative parameters and time-relative-intensity curve（TRIC） in malignant and benign liver tumors with contrast-enhanced ultrasound（CEUS）. Methods Fifty-nine focal liver lesions were examined with CEUS and drawed time-intensity curve（TIC） with QLAB software. The relative parameters of malignant and benign liver tumors were calculated and analysed. The relative intensity equaled the echo intensity of lesion substracted the encho intensity of liver. TRIC were drawed with time as abscissa and relative intensity as the ordinate. The types of TIRC were analysed comparatively in different groups （benign and malignant）. Results There were significant differences in relative peak time, relative peak intensity, relative enhancement time and relative decline slope between malignant and benign lesions（ P 〈0. 05）. TRIC appeared quick-ascending and quick-descending types in the malignant lesions,the decline curve of TRIC droped down to 0 dB at （28.24 ± 8. 14）s and down to lowest - 8 dB continually, meanwhile fluctuated slightly. While TRIC appeared slow-ascending and slow-descending types in the benign lesions, the decline curve of TRIC droped down to the lowest 4 dB continually, meanwhile fluctuated slightly. Conclusions The relative parameters and TRIC are new quantitative indicators of CEUS for diagnosis of malignant and benign liver tumors.

关 键 词：超声检查 微气泡 肝肿瘤 

分 类 号：R686[医药卫生—骨科学]