三维超声检测子宫内膜及内膜下血流评估体外受精-胚胎移植中子宫内膜容受性的价值  

Role of endometrial and subendometrial blood flows measured by three-dimensional power Doppler ultrasound in the prediction of endometrial receptivity during IVF-ET treatment

作　　者：王锦惠[1] 门殿霞[1] 于子芳 闫芳[1] 李春敏[1] 肖文丽[1] 刘英[1] 张烁[2] 

机构地区：[1]太原市第二人民医院超声诊断科,030002 [2]太原市中心医院生殖中心

出　　处：《中华超声影像学杂志》2010年第10期878-881,共4页Chinese Journal of Ultrasonography

基　　金：基金项目：太原市科技局科技兴市项目（0802055）

摘　　要：目的 探讨经阴道三维能量多普勒超声检测子宫内膜及内膜下血流对体外受精与胚胎移植（IVF-ET）中子宫内膜容受性的预测价值.方法 应用经阴道三维能量多普勒超声,对120例接受IVFET的不孕患者,于控制性超排卵（COH）周期人绒毛膜促性腺激素（HCG）注射日进行子宫内膜厚度、内膜容积、内膜及内膜下区域的血管化指数（VI）、血流指数（FI）、血管化血流指数（VFI）测定,根据妊娠结果分为妊娠组与未妊娠组,比较两组间各参数的差异.结果 120例患者中有2例未检测到内膜血流,2例未检测到内膜下血流,1例未检测到内膜及内膜下血流,其余115例内膜和内膜下血流均显示.120例患者临床妊娠39例,妊娠率32.5%,妊娠组内膜及内膜下VI、FI、VFI均高于未妊娠组,两组间VI、FI、VFI比较差异有统计学意义（P＜0.05）.内膜及内膜下VI、FI、VFI预测妊娠的ROC曲线下面积分别为0.729、0.670、0.655及0.720、0.715、0.617.结论 经阴道三维能量多普勒超声检测子宫内膜及内膜下血流可以预测子宫内膜容受性,评估IVF-ET结局.Objective To investigate the role of endometrial and subendometrial blood flows measured by transvaginal three-dimensional（3D） power Doppler ultrasound in the prediction of endometrial receptivity during in vitro fertilization-embryo transfer （IVF-ET） cycles. Methods One hundred and twenty patients undergoing IVF-ET cycles were enrolled in this study. Transvaginal 3D power Doppler ultrasound examination was performed on the day of human chorionic gonadotropin injection to determine endometrial thickness,endometrial volume, vascularization index（VI）, flow index（FI） and vascularization flow index （VFI） of endometrial and subendometrial regions by experienced sonograpbers. The patients were divided into pregnant group and non-pregnant group according to pregnant outcome. The data between the two groups were compared and analysed. Results There were no significant differences（ P 〉0.05） between the pregnant group and non-pregnant group in endometrial thickness, endometrial volume. Endometrial and subendometrial VI,FI, VFI were higher in the pregnant group than those in the non-pregnant group, and statistical comparison had significant difference（ P 〈0.05）. Conclusions Endometrial and subendometrial blood flows measured by transvaginal 3D power Doppler ultrasound can be as a reliable indicator to assess endometrial receptivity and to predict the pregnancy outcome.

关 键 词：腔内超声检查 子宫内膜 受精 体外 胚胎移植 

分 类 号：R686[医药卫生—骨科学]