超声在兔股动脉血栓模型评价中的价值  

Value of ultrasonography in evaluating the femoral artery thrombosis in rabbits

作　　者：郭朝锋[1] 穆玉明[1] 关丽娜[1] 唐琪[1] 

机构地区：[1]新疆医科大学第一附属医院超声医学中心心脏超声诊断科,乌鲁木齐830054

出　　处：《中华超声影像学杂志》2010年第10期901-904,共4页Chinese Journal of Ultrasonography

基　　金：基金项目：国家自然科学基金资助项目（30860267）

摘　　要：目的 探讨超声在兔股动脉血栓模型评价中的应用价值.方法 选取20只新西兰大白兔,应用三氯化铁外敷联合夹闭法建立兔双侧股动脉血栓模型,用超声和血流仪评价血栓形成情况,以病理结果作为金标准,分析两种方法与病理结果的一致性.结果 共32条股动脉成功建立血栓模型,其中19条股动脉形成闭塞性血栓.超声诊断血栓形成与病理结果高度一致（Kappa值0.720,P＜0.001） 血流仪诊断血栓形成与病理结果中度一致（Kappa值0.546,P＜0.001）.超声和血流仪诊断闭塞性血栓形成与病理结果均高度一致（Kappa值分别为0.800、0.798,P均＜0.001）.结论 超声在兔动脉血栓模型评价中与病理结果具有高度的一致性,在非闭塞性血栓的诊断中优于血流仪诊断.Objective To investigate the value of ultrasonography in evaluating the femoral artery thrombosis in rabbit. Methods Thrombosis was induced by external application with 10% ferric chloride and transient femoral artery-occlusion with bulldog clamp in twenty New-Zealand rabbits. The thrombosis was monitored by both Doppler flowmeter and ultrasonography. The histopathological result was used as the golden standard. The consistency of the above two results with the golden standard was analyzed. Results Thirty-two femoral arteries thrombosis were produced successfully. There was high consistency between the results of ultrasonic evaluation and histopathological examination （Kappa = 0. 720, P 〈 0. 001 ）, and moderate consistency between the results of Doppler flowmeter evaluation and histopathological examination （Kappa = 0. 546, P 〈0. 001 ）. Within the thirty-two femoral arteries thrombosis, there were nineteen arteries with occlusive thrombus examined by histopathological means. Both the results of Doppler flowmeter and ultrasonography were highly consistent with the results of histopathological examination （Kappa = 0. 800 and 0.798 respectively, P 〈 0. 001 ）. Conclusions There is high consistency between the results of ultrasonic evaluation and histopathological examination for the common femoral artery thrombosis in rabbit.In the non-occlusive thrombus diagnosing,ultrasonography is better than Doppler flowmeter.

关 键 词：超声检查 血栓形成 兔 股动脉 

分 类 号：R686[医药卫生—骨科学]