辛伐他汀治疗高脂血症50例疗效观察  

Effect of simvastatin on hyperlipoidemia

作　　者：陈兰[1] 

机构地区：[1]海南省东方市人民医院内科,海南东方572600

出　　处：《海南医学院学报》2010年第9期1170-1171,1176,共3页Journal of Hainan Medical University

基　　金：海南医学院科研基金资助学报项目(0020100325)~~

摘　　要：目的:观察辛伐他汀治疗高脂血症的临床效果。方法:选择原发性高脂血症100例,随机分为两组,治疗组与对照组各50例,对照组给予口服血脂康片,每次2片,3次/d;治疗组给予晚餐后顿服辛伐他汀20mg,1次/d,总疗程8周,观察两组血脂变化。结果:治疗8周后治疗组的总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)均较对照组明显降低(P<0.05),高密度脂蛋白胆固醇(HDL-C)较对照组明显升高(P<0.05)。结论:辛伐他汀降血脂作用明显、快速、安全、可靠。Objective：To observe the effect of simvastatin on hyperlipoidemia.Methods：A total of 100 cases with primary hyperlipoidemia were randomly divided into treatment group and control group by half.Cases in control group were treated with Xuezhikang tablets,two tablets once,three times a day for 4 weeks,while the treatment group received simvastatin 20 mg after supper once a day for 8 weeks.The lipid changes were observed.Results：The treatment group showed significantly lower level of total cholesterine,glycerine,low density lipoprotein cholesterol and higher high density lipoprotein cholesterol than the control group（P both〈0.05）.Conclusions：Simvastatin is rapid,safe and reliable option for hyperlipoidemia.

关 键 词：辛伐他汀 高脂血症 血脂康片 

分 类 号：R54[医药卫生—心血管疾病]