C反应蛋白在颈腰椎间盘突出症微创术后椎间隙感染鉴别中的应用  

The application of C-reactive protein in a intervertebral space infection after minimally invasive operation of prolapse of cervical and lumbar intervertebral disc

作　　者：纪新梅[1] 贾冰[1] 仇思武[1] 李启中 

机构地区：[1]肇庆市第一人民医院检验科 [2]高要市人民医院骨外科

出　　处：《国际医药卫生导报》2010年第22期2752-2753,共2页International Medicine and Health Guidance News

摘　　要：目的 探讨C反应蛋白在颈腰椎间盘突出症微创术后早期椎间隙感染鉴别中的临床意义.方法 选择2009年5月-2010年5月在我院住院的颈腰椎间盘突出症微创术后患者150例,其中确诊椎间隙感染21例（男15例,女6例,年龄35～76岁,平均56岁）,其余患者均如期痊愈出院.将150例患者分为感染组和对照组.设备使用德国罗氏公司COBAS INTEGRA400型全自动生化分析仪进行血清C反应蛋白及WBC测定,试剂采用德国罗氏公司原装配套产品.采用免疫比浊法,空腹抽取静脉血,分离血清,2小时内完成检测.结果 21例微创术后椎间隙感染患者早期白细胞总数（WBC）均在正常值内,而患者C反应蛋白（CRP）明显高于正常值,均超过40mg/L.结论 C反应蛋白在颈腰椎间盘突出症微创术后,椎间隙感染的早期诊断中具有显著的临床意义,为后期的临床治疗提供有效的监测数据.Objective To investigate the clinical significance of C-reactive protein used for identification in an early stage of the intervertebral space whether to have become infect or not after minimally invasive operation of prolapse of cervical and lumbar intervertebral disc. Methods We collect 21 patients, including 15 men and 6 women, the age group of 35 to 76 years old , and the average age of the group is 56. The equipment used is the German Roche Campus COBAS INTEGRA 400, and yuan ding supplies us with reagents. Results The leukocyte count （wbc） of 21 cases whose intervertebral space infect after minimally invasive operation are within normal range early, while C-reactive protein （ckp） is significantly higher than normal, and it is more than 40m / L. Conclusion C-reactive protein is significant for earlydiagnosis when people＇s intervertebral space infect after minimally invasive operation, and it can provide the follow-up clinical treatment with effective monitoring data

关 键 词：C反应蛋白 颈腰椎间盘 微创术后 椎间隙感染 鉴别诊断 

分 类 号：R687.3[医药卫生—骨科学]