39例头孢唑肟钠注射剂的不良反应分析  

Adverse reactions of ceftizoxime sodium injection in 39 patients

作　　者：黄妙婵[1] 

机构地区：[1]东莞市人民医院药剂科,523018

出　　处：《国际医药卫生导报》2010年第21期2642-2644,共3页International Medicine and Health Guidance News

摘　　要：目的 通过对39例头孢唑肟钠注射剂引起的不良反应报告进行分析,探讨头孢唑肟钠注射剂不良反应发生的规律和临床表现,提示临床注意监测其不良反应,避免严重后果.方法 对39例头孢唑肟钠注射剂引起的不良反应进行统计和分析.结果 女22例,男17例,女性多于男性;患者年龄在0～50岁之间,其中10岁以下儿童发生率最高,为46.15%;静脉滴注给药38例（97.44%）,肌内注射给药1例（2.56%）;头孢唑肟钠注射剂的主要不良反应是过敏反应（66.67%）,此外还可引起过敏性休克、呼吸系统损害等较少见的、严重的不良反应.结论 要合理使用头孢唑肟钠注射剂,避免和减少不良反应的发生.Objective To explore the incidence and clinical manifestations of ceftizoxime sodium-associated adverse reactions by analyzing the reports of adverse reactions caused by 39 cases of ceftizoxime sodium injections, this thesis aims at exploring the law of adverse reactions and of ceftizoxime sodium injection, reminding clinical treatment to monitor the adverse reactions to avoid serious consequences.Methods The adverse reactions caused by ceftizoxime sodium injections in 39 patients were analyzed statisticcally. Results More adverse reactions occurred in females than in males（ 22 vs 17 ）. The patients was 0 to 50 years old, mostly children younger than 10 （ 46.15% ）. 38 patients （ 97.44% ） were due to intravenous drip and one （ 2.56% ） due to tointramuscular injection. The main adverse reaction was allergic reaction（66.67% ） in addition, other rare and severe adverse reactions including anaphylactic shock and respiratory damage could developed. Conclusions Ceftizoxime sodium injections should be rationally used

关 键 词：头孢唑肟钠 不良反应(ADR) 临床分析 

分 类 号：R9[医药卫生—药学]