固相萃取-气质联用法检测上海市不同水厂各处理工艺环节水中几种除草剂、杀菌剂和雌激素水平  

Determination of several herbicides, fungicides and estrogens in water from various treatment processes of different water plants in Shanghai by solid phase extraction-gas chromatography/mass spectrometry

作　　者：郑唯韡[1] 王霞[1] 田大军[1] 韦霄[1] 陈鑫[1] 张皓[1] 周颖[1] 刘莉[1] 郭帅[1] 蒋颂辉[1] 屈卫东[1] 

机构地区：[1]复旦大学公共卫生学院环境卫生学教研室公共卫生安全教育部重点实验室,上海200032

出　　处：《中华预防医学杂志》2010年第10期899-902,共4页Chinese Journal of Preventive Medicine

基　　金：国家科技支撑计划（2006BAI19B02、2008ZX07421-004）;国家高技术研究发展计划（2008AA062501）

摘　　要：目的 建立应用固相萃取-气质联用法定性定量检测饮用水中几种除草剂、杀菌剂和雌激素的方法.方法 采集不同水厂各工艺环节水样各1 L,每点设2个平行样,以XAD-2树脂富集水样中目标污染物,30%丙酮-甲醇洗脱,采用气相色谱-质谱联用仪（GC/MS）对目标污染物定性定量分析.结果 6种待测物质（莠去津、甲草胺、4-枯基酚、噻苯咪唑、β-雌二醇、乙炔雌二醇）标准曲线线性范围为0.1～10 μg/ml,R2为0.9915～0.9995,检出限为0.01～0.40 μg/L,加标回收率为74.0%～112.0%,相对标准偏差（RSD）为2.3%～14.8%.黄浦江水源的原水、混凝后水、沉淀后水和出厂水中均可检出莠去津（0.11～0.13 μg/L）、4-枯基酚（0.20～0.35 μg/L）、噻苯咪唑（0.96～1.66 μg/L）、β-雌二醇（1.02～1.32 μg/L）、乙炔雌二醇（0.92～1.46 μg/L）,各水样中均未检测到甲草胺.长江水源水厂各水样中均未检出6种污染物.结论 本方法灵敏度高、选择性好,适合于饮用水中目标污染物的同时定性定量分析.黄浦江水源饮用水中上述污染物浓度明显高于长江水源饮用水.黄浦江为水源的饮用水中存在μg/L级的噻苯咪唑、β-雌二醇、乙炔雌二醇应该在今后的监测工作中引起重视.Objective To establish the solid phase extraction-gas chromatography/mass spectrometry （GC/MS） method for qualitative and quantitative determination of several herbicides ,fungicides and estrogens in drinking water. Methods Duplicate 1 L water samples were collected from various treatment processes of different water plants. Target pollutants were extracted by XAD-2 resin from water samples and were eluted by 30% acetone-methanol. GC/MS was employed for qualitative and quantitative analysis of target pollutants. Results The linear ranges of standard curves of 6 target compounds including atrazine, alachlor,4-cumyphenol, thiabendazole, β-estradiol and ethylestradiol were 0.1 - 10 μg/ml and the R2 values were 0.9915 -0.9995. The detection limits,the recovery rates,and the relative standard deviation （RSD） were separately 0.01 -0.40 μg/L,74.0% - 112.0% and 2.3% - 14.8%. Atrazine （0.11 -0.13 μg/L） ,4-cumyphenol （0.20 - 0.35 μg/L）, thiabendazole （ 0.92 - 1.46 g/L ）, β-estradiol （ 1.02 -1.32 μg/L） and ethylestradiol（0.96 - 1.66 μg/L） were all detected in raw water, post-coagulation water,post-sedimentation water and finished water using Huangpu River as water source. Alachlor was not detected in any water samples in Huangpu River. The 6 target compounds were not detected in any water samples from the water plants using Yangtse River as water source. Conclusion The methods with high sensitivity and satisfying selectivity are suitable to simultaneously qualitative and quantitative determination of target pollutants in drinking water. Concentrations of above-mentioned pollutants in drinking water coming from Huangpu River are obviously higher than in drinking water coming from Yangtze River. Thiabendazole,β-estradiol and ethylestradiol at the level of μg/L exist in drinking water coming from Huangpu River and more attention should be paid to surveillances of future.

关 键 词：水 碎片质谱法 环境监测 

分 类 号：R686[医药卫生—骨科学]