氧氟沙星及其片剂的分光光度测定  

SPECTROPHOTOMETRY OF OFLOXACIN AND ITS TABLETS

作　　者：王磊[1] 张延岭[1] 刘新泳[1] 李忠[1] 桑立红 周洪 

机构地区：[1]山东医科大学药学系

出　　处：《中国医药工业杂志》1999年第5期224-225,共2页Chinese Journal of Pharmaceuticals

摘　　要：在二甲亚砜－甲醇介质中氧氟沙星与三价铁离子可形成稳定的橙红色配合物，其最大吸收波长为４２０ｎｍ，可采用分光光度测定氧氟沙星及其片剂的含量，结果准确可靠。Offoxacin and its tablets were measured by spectrophotometry, based on the formation of the orange complex by ofloxacin with ferric chloride in dimethylsulphoxide methanol, which exhibited maximum absorbance at 420 nm. The linear range was 25￣150 μg/ml. The average recovery was 99.78% with RSD of 0.19% ( n =6).

关 键 词：氧氟沙星 片剂 分光光度法 测定 

分 类 号：R978.19[医药卫生—药品] R927.2[医药卫生—药学]