83例静脉药瘾者的TT病毒感染状况  

Detection of TT virus in 83 intravenous drug users

作　　者：李建国[1] 周元平[1] 姚春兰[1] 黄仰苏[1] 高志良[1] 

机构地区：[1]中山医科大学附属第三医院传染科,510630

出　　处：《新医学》1999年第6期320-321,共2页Journal of New Medicine

基　　金：广东省自然科学基金!940231

摘　　要：调查静脉药瘾者中TT病毒（TTV）的感染状况。方法：在TT病毒开放读码框（ORF）1保守区设计引物，建立巢式PCR，检测83例静脉药瘾者和105名献血员血清中TTVDNA。结果：83例静脉药瘾者中33例TTVDNA阳性，阳性中为40％，而献血员的阳性率为11％（P＜0．05）、结论：静脉药瘾者是TT病毒感染的高危人群，不洁注射是感染TT病毒的重要途径。Objective: To investigate the prevalence of TT virus (TTV) infection in intravenous drug users(IVDU ) Method: A nested polymerase chain reaction (PCR) assay with primers from ORF1 of TTV genome was established to detect TTV DNA in the serum samples of 83 IVDU and 105 blood donors. Result: 33 of the 83 (40% ) IVDU and 12 of 105 (11%) blood donors were positive for TTV DNA (P<0. 05) Conclusion: IVDU is highly risk population for TTV infection and the contaminated injection plays an important role in the transmission of TTV.

关 键 词：静脉药瘾 TT病毒感染 聚合酶链反应 

分 类 号：R512.6[医药卫生—内科学]