经气管镜针吸活检术和经气管镜超声引导针吸活检术在结节病诊断中的价值  

Diagnostic Value of Transbronchial Needle Aspiration and Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in Sarcoidosis

作　　者：张嵩[1] 马卫霞[1] 姜淑娟[1] 李元堂[2] 彭忠民[3] 王永康[4] 

机构地区：[1]山东大学附属省立医院呼吸内科,山东济南250021 [2]山东大学附属省立医院细胞室,山东济南250021 [3]山东大学附属省立医院胸外科,山东济南250021 [4]山东大学附属省立医院病理科,山东济南250021

出　　处：《临床肺科杂志》2010年第12期1686-1688,共3页Journal of Clinical Pulmonary Medicine

基　　金：山东省科技发展计划项目(编号:2009GG10002061)

摘　　要：目的探讨经气管镜针吸活检术(TBNA)和经气管镜超声引导针吸活检术(EBUS-TBNA)在结节病诊断中的价值。方法选取15例临床表现和胸部CT检查疑似结节病患者,同时行TBNA和纵隔镜检查。另选取20例疑似结节病的患者行EBUS-TBNA检查。结果 15例同时行TBNA和纵隔镜检查患者中诊断为结节病的12例,TBNA诊断阳性率83.33%(10/12);20例行EBUS-TBNA患者中诊断为结节病的18例,EBUS-TBNA诊断阳性率为88.89%(16/18)。结论 EBUS-TBNA和TBNA创伤性小、安全性好,在结节病的诊断中有较高的应用价值。Objective To investigate the significance of endobronchial ultrasound-guided transbronchial needle aspiration（EBUS-TBNA） in diagnosing sarcoidosis.Methods TBNA and mediastinoscopy procedures were performed in 15 consecutive patients who had mediastinal and/or hilar adenopathy with or without pulmonary abnormalities identified on CT of the chest,referred for suspected pulmonary sarcoidosis clinically.20 other undiagnosed patients suspected pulmonary sarcoidosis clinically were performed with EBUS-TBNA.Results Adequate lymph node sampling was obtained from the 15 patients.12 patients were diagnosed by mediastinoscopy.We were able to make a diagnosis by cytologically,which included sarcoidosis（n = 10,83.33%）.In addition,The same result was obtained from 20 patients performed with EBUS-TBNA,including sarcoidosis in 16 patients（88.89%,16 /18）.Conclusion EBUS-TBNA and TBNA is an effective and safe way of obtaining cytologic specimens from intrathoracic lymph nodes and can rapidly provide diagnosis in sarcoidosis diseases.

关 键 词：经气管镜超声引导针吸活检术 结节病 气管镜 纵隔镜 

分 类 号：R593.2[医药卫生—内科学]