三联疗法治疗慢性荨麻疹疗效观察  

Triple Therapy for Chronic Urticaria

作　　者：黄德顺[1] 刘恩让[1] 廉翠红[1] 

机构地区：[1]深圳市第二人民医院皮肤性病科,深圳518035

出　　处：《中国医院用药评价与分析》2010年第10期917-918,共2页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:观察曲普利啶、复方甘草酸苷和雷尼替丁联合治疗慢性荨麻疹的疗效。方法:将门诊确诊为慢性荨麻疹的患者随机分为两组:治疗组66例(口服曲普利啶、复方甘草酸苷和雷尼替丁)和对照组66例(口服曲普利啶)。疗程为4周,停药1周后随诊观察疗效。结果:治疗组的治愈率为65.2%,总有效率为93.9%;对照组的治愈率为30.3%,总有效率为80.3%;两组的治愈率和有效率比较有显著性差异。结论:口服曲普利啶联合复方甘草酸苷、雷尼替丁治疗慢性荨麻疹效果好,值得临床应用。OBJECTIVE：To observe the curative efficacy of Triprolidine in combination with Compound glycyrrhizin and Ranitidine for chronic urticaria.METHODS：The outpatients confirmed as having chronic urticaria were randomized to either treatment group（n = 66） receiving Compound glycyrrhizin and Ranitidine or the control group（n = 66） receiving oral Triprolidine alone all for 4 weeks.The clinical efficacy was observed in at 1 week after drug discontinuation.RESULTS：There were significant differences between the two groups in cure rate（65.2% vs.30.3%） and the total effective rate（93.9% vs.80.3%）.CONCLUSION：Triprolidine associated with Compound glycyrrhizin and Ranitidine is effective for chronic urticaria,hence the combination therapy is worthy of being recommended in clinical practice.

关 键 词：慢性荨麻疹 曲普利啶 复方甘草酸苷 雷尼替丁 

分 类 号：R979.5[医药卫生—药品]