大蒜提取液联合环丙沙星对铜绿假单胞菌PAO1、PAO-JP2浮游菌抗菌作用的研究  

Study on Anfibacferial Function of Garlic Extracts Combined with Gprofloxacin on PAO1,PAO-JP2

作　　者：梁群[1] 杨滢[2] 秦国琦[2] 瞿伟[2] 

机构地区：[1]黑龙江中医药大学附属第一医院,黑龙江哈尔滨150040 [2]黑龙江中医药大学,黑龙江哈尔滨150040

出　　处：《中医药信息》2010年第5期35-36,共2页Information on Traditional Chinese Medicine

基　　金：哈尔滨市科学研究基金项目(11513107)

摘　　要：目的:测定大蒜提取液、喹诺酮类药物对PAO1、PAO-JP2浮游菌最低抑菌浓度,探讨两株菌对抗菌药物敏感性差异。方法:采用棋盘法设计,空白组、大蒜组、环丙沙星组、大蒜和环丙沙星组。结果:大蒜提取液对PAO1浮游菌MIC值高于PAO-JP2。结论:大蒜提取液和环丙沙星联用后,能明显降低该两种抗生素对铜绿假单胞菌PAO1、PAO-JP2的MIC值,大蒜提取液与环丙沙星联用后,抗菌效果以协同效应。Objective：The determination garlic extracts,kui the ketones medicine to PAO1,the PAO-JP2 float fungus lowest bacteriostasis density,discusses two fungi to the antibiotics sensitive difference.Methods：Uses the checkerboard law design,the blank group,the garlic group,ciprofloxacim,the garlic and ciprofloxacim.Results： The garlic extracts to PAO1 the float fungus MIC value is higher than PAO-JP2.Conclusion： The garlic extracts with cyclopropane Sha Xinglian,can reduce these two kind of antibiotics obviously to verdigris pseudomonad PAO1,the PAO-JP2 MIC value,the garlic extracts with cyclopropane Sha Xinglian,antibacterial effect cooperative effect.

关 键 词：大蒜提取液 铜绿假单胞菌 抗菌作用 

分 类 号：R515[医药卫生—内科学]