乙酰苯胺制备的绿色化研究  

Synthesis of Acetanilide under Greener Conditions

作　　者：张力[1] 李康兰[1] 白林[1] 

机构地区：[1]兰州城市学院绿色化学实验与教学研究所,甘肃兰州730070

出　　处：《甘肃高师学报》2010年第5期16-18,共3页Journal of Gansu Normal Colleges

基　　金：兰州城市学院绿色化学与环境保护重点学科建设项目

摘　　要：采用苯胺和冰醋酸(乙酸酐)为原料,通过分馏法、回流法、干燥法、回流-干燥法、微波辐射法合成了乙酰苯胺.从绿色化学理念出发,进行反应方法探究和比较,优选出合理、实用、可行的制备方法.回流-干燥法和微波法是较佳的合成方法,不仅操作简便,反应时间缩短,而且提高了反应产率,使实验操作更加绿色化,也可为探究性实验的设计提供借鉴.Acetanilide can be prepared from aniline in several ways,using glacial acetic acid or acetic anhydride as starting materials.The fractional distillation,reflux,dry distillation,reflux-dry distillation and microwave irradiation heat are present methods.From both green chemistry point of view and experimental procedure,the reflux-dry distillation is preferred for laboratory synthesis because their notable improvement in shorting time,improving yield and simplifying procedure.

关 键 词：乙酰苯胺 回流-干燥法 微波辐射 绿色化学实验 

分 类 号：O62-3[理学—有机化学]