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机构地区:[1]上海交通大学安泰经济与管理学院,上海200043 [2]上海交通大学医学院附属第三人民医院医务部,上海201900
出 处:《药学服务与研究》2010年第5期354-356,共3页Pharmaceutical Care and Research
基 金:上海市教育委员会资助项目(No.09YS109);上海市宝山区科学技术委员会基金立项课题(No.08-E-2)
摘 要:目的:设计一个简单易行的药品不良反应(ADR)伤害程度量化分级评分标准,为构建ADR补偿体系服务。方法:遴选部分专家,对不同器官和不同层级的ADR伤害进行评分。ADR伤害由重到轻初步分为1~10级,1级为最严重伤害,10级为最轻微伤害,根据评分结果进行统计分级。结果:ADR损害评分如下。极轻度伤害:>8.20分,轻度伤害:7.05~8.20分,中度伤害:4.31~7.04分,重度伤害:2.79~4.30分,极重度伤害:≤2.78,死亡单独作为一级。结论:这一分级方法可行,可以为进一步的ADR伤害量化研究提供借鉴。Objective:To establish a simple and practical criteria for quantitative classification of adverse drug reaction(ADR) injuries and provide reference for construction of the ADR compensation system.Methods:Some experts were invited to evaluate the degrees of ADR injuries to different organs and systems.Grade 1 to 10 were used for various degrees of severity of injury.Grade-1 implied death and grade-10 implied the slightest injury.The classification criteria were established according to the scores.Results:The ADR injuries were ranked into 6 levels.The score criteria for extremely slight,slight,moderate,severe and extremely severe injuries were8.20,7.05-8.20,4.31-7.04,2.79-4.30 and ≤2.78,respectively,and death was another level alone.Conclusion:The classification criteria are feasible and useful for further study.
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