骨组织工程支架渐变孔洞的设计  

Gradient Holes Design of Bone Tissue Engineering Scaffolds

作　　者：张厚安[1] 龚兰云[2] 高永毅[3] 

机构地区：[1]厦门理工学院材料制备与应用技术研究所,福建厦门361024 [2]湖南电气职业技术学院机械系,湖南湘潭411101 [3]湖南科技大学先进材料制备与应用研究所,湖南湘潭411201

出　　处：《厦门理工学院学报》2010年第3期34-37,共4页Journal of Xiamen University of Technology

基　　金：湖南省自然科学基金(05JJ30079);湖南省教育厅项目(2008FJ3037)

摘　　要：根据自然骨组织的微观结构特点,建立了一种圆柱状骨支架模型,它由圆环骨板、变截面圆杆和变截面孔洞组成.其中变截面圆杆将圆环骨板连接起来,变截面孔洞使骨板连通.通过胞元力学模型分析得出,胞元旋转角度呈0°排列较好;当圆杆和孔的直径减少和数量相应增加时,胞元的最大等效应力相应减小.According to the characteristics of the microscopic structure of bone tissue,a cylinder-shaped bone scaffold is established.It consists of ring plates and variable cross-section rods and variable cross-section holes,and the ring plates are connected by variable cross-section rods and variable cross-section holes.By the unit cell finite element model analysis,the bearing capacity of the unit is better at 0 ° rotation angle.When the rods and the holes diameter decrease and their numbers increase,the maximum equivalent stress get lower accordingly.

关 键 词：骨组织工程 骨支架模型 渐变孔洞 

分 类 号：R318.08[医药卫生—生物医学工程]