黄连及其炮制品水分灰分和浸出物的测定  

Determination of Moistures,Total Ashes,and Ethanol Extracts of Crude and Processed Rhizoma of Coptidis

作　　者：王欣[1] 武小赟[2] 李铁钢[2] 阳勇[1] 钟国跃[1] 范昕建[2] 秦松云[1] 张艺[2] 罗维早[1] 

机构地区：[1]重庆市中药研究院,重庆400065 [2]成都中医药大学,四川成都611730

出　　处：《时珍国医国药》2010年第10期2498-2500,共3页Lishizhen Medicine and Materia Medica Research

基　　金：国家科技支撑计划项目(No.2007BAI40B05);<中国药典>2010版姜黄连炮制品标准制定(YZ251;YZ252;YZ253);<中国药典>2010版黄连饮片标准制定

摘　　要：目的对不同来源的黄连及其炮制品的水分、灰分和浸出物进行测定,为2010年版《中国药典》黄连及其炮制品制订相关的质量标准。方法按2005年版《中国药典》附录IXH水分测定法第1法、附录IXK灰分测定法、附录XA浸出物测定法测定。结果黄连原药的水分不得过14.0%,总灰分不得过5.0%,50%乙醇热浸出量不得少于18.5%;黄连饮片的水分不得过12.0%,总灰分不得过3.0%,50%乙醇热浸出量不得少于17.0%;酒黄连饮片的水分不得过10.0%,总灰分不得过3.5%,50%乙醇热浸出量不得少于17.0%;姜黄连饮片的水分不得过11.0%,总灰分不得过3.5%,50%乙醇热浸出量不得少于18.0%;萸黄连饮片的水分不得过11.0%,总灰分不得过3.5%,50%乙醇热浸出量不得少于17.0%。结论其研究结果可用于2010年版《中国药典》黄连及其炮制品质量标准的制定。Objective To determine the moistures,total ashes,and ethanol extracts of the crude and processed rhizome of Coptidis with different resources,in order to establish the quality standards of Chinese Pharmacopoeia of 2010 edition. Methods According to the appendix IX H,IX K and X A of Chinese Pharmacopoeia of 2005 edition,the moistures,ashes,and enthanol extracts of the crude and processed rhizoma of Coptidis were determined respectively. Results The moisture in Coptidis was less than 14. 0% ,with the total ash within 5. 0% ,and the 50% ethanol extract was not less than 18. 5% by hot soak. The moisture in Huanglian Yinpian was less than 12. 0% ,with the total ash within 3. 0% ,the 50% ethanol extract was less than 17. 0% by hot soak. The moisture in Jiuhuanglian was less than 10% ,with the total ash within 3. 5% ,the 50% ethanol extract was less than 17. 0% by hot soak. The moisture in Jianghuanglian was less than 11. 0% ,with the total ash within 3. 5% ,the 50% ethanol extract was less than 18. 0% by hot soak. The moisture in Yuhuanglian was less than 11% ,with the total ash within 3. 5% , the 50% ethanol extract was not less than 17. 0% by hot soak. Conclusion The results might be used to the quality standards of the crude and processed rhizoma of Coptidis about the moisture,total ash,and ethanol extract for editing Chinese Pharmacopoeia of 2010 edition.

关 键 词：黄连 黄连饮片 酒黄连 姜黄连 萸黄连 水分 灰分 浸出物 

分 类 号：R283[医药卫生—中药学]