广东省60岁以上心内科住院患者10年血脂异常调查  

Prevalence of dyslipidemia in old patients with cardiovascular diseases:a survey for 10-year period in Guangdong Province

作　　者：周云[1] 刘丰[1] 吴剑芸[1] 黄为民[1] 李庆云[1] 林添海[1] 张韶刚[1] 

机构地区：[1]广州医学院附属广州市第一人民医院老年科,广州510180

出　　处：《广东医学》2010年第16期2143-2146,共4页Guangdong Medical Journal

摘　　要：目的调查广东省1995年和2005年60岁以上心内科住院患者血脂异常情况,了解10年间血脂水平及血脂异常患病率的变化。方法采取整群抽样的方法,将广东省10个城市的16所三甲医院1995年和2005年心内科60岁以上住院患者作为研究样本(4714人),将研究对象按年龄(岁)分为60～69、70～79、80及以上3组。对所有患者血脂结果进行回顾性分析。结果 (1)2005年血清TG、TC、LDL-C平均水平低于1995年,60～69岁组最高,且随着年龄的增大,均值逐渐减小(P<0.05)。(2)2005年高LDL-C血症和低HDL-C血症的患病率明显低于1995年(P<0.01),高TG血症、高TC血症患病率差异无统计学意义;1995年和2005年高TG血症、高TC血症、高LDL-C血症女性患病率均明显高于男性(P<0.01);1995年和2005年各年龄组血脂异常的患病均以60～69岁、70～79岁组占比例大。结论广东省60岁以上心内科住院患者10年间血脂水平、血脂异常患病率均明显下降,且存在性别及年龄差异,应根据不同性别及年龄进行有针对性的防治。Objective To study the blood lipid abnormality in patients over 60 years old with cardiovascular diseases in Guangdong province and investigate its changes over the 10 years from 1995 to 2005.Methods By the means of the cluster sampling,4714 patients over 60 years old were enrolled from patients admitted in the Department of Cardiology of the 16 Grade III-A hospitals in Guangdong Province between 1995 and 2005 and divided into the groups of 60～69,70～79 and over 80 years old.The plasma lipid levels were analyzed statistically.Results（1）TG,TC and LDL-C levels were significantly lower in the patients surveyed in 2005 than in those surveyed in 1995.Plasma lipid level was significantly reduced with age in patients surveyed in 2005（P0.05）.（2）Significantly lower prevalence of high blood LDL-C and low blood HDL-C was observed in patients surveyed in 2005 compared with 1995（P0.01）,while no significant difference was observed in prevalence of hypertriglyceridemia and hypercholesterolemia between 1995 and 2005.Furthermore,significantly higher prevalence of hypertriglyceridemia and hypercholesterolemia was presented in females in both 1995 and 2005（P0.01）.Patients with age between 60 and 79 comprised the majority of hyperlipidemia population in both 1995 and 2005.Conclusion Over 10 years,the prevalence of dyslipidemia has decreased in patients over 60 years old with cardiovascular diseases in Guangdong province with reduced serum lipid levels.Furthermore,there is different prevalence of dyslipidemia in different sex and age;Diverse strategy is needed for its prevention and treatment in old population.

关 键 词：血脂异常 患病率 心血管疾病 流行病学 老年人 

分 类 号：R473.5[医药卫生—护理学]