电子支气管镜检查对弥漫性肺间质性疾病的诊断价值  

Diagnostic value of electronic bronchoscopy in diffuse interstitial lung diseases

作　　者：夏宇[1] 曾敏[2] 郗慧[1] 何元兵[1] 齐曼古力.吾守尔 

机构地区：[1]新疆医科大学第一附属医院呼吸科,新疆乌鲁木齐830011 [2]新疆医科大学附属肿瘤医院胸腹放疗科,新疆乌鲁木齐830011

出　　处：《新疆医科大学学报》2010年第8期906-909,共4页Journal of Xinjiang Medical University

基　　金：新疆维吾尔自治区重点学科(内科学)建设经费(2004-2008)资助

摘　　要：目的探讨电子支气管镜检查联合多种取材方法对弥漫性肺间质性病变(ILD)的临床诊断价值。方法经痰细胞学及细菌学检查均为阴性的弥漫性肺间质性病变129例行电子支气管镜检查,并做镜下钳夹、经支气管肺活检(TBLB)、支气管镜下针吸活检(TBNA)、灌洗(BAL)及刷片(BB)检查,对以上方法的诊断价值进行分析。结果经上述方法确诊特发性肺纤维化64例(49.6%),继发性肺纤维化13例(10.1%),肺癌17例(13.2%),肺结核7例(5.4%)及其它少见的肺部疾病。未能明确诊断者共18例(14.0%);电子支气管镜检查联合多种取材方法较初次TBLB确诊率显著提高,差异有统计学意义(P<0.05)。结论电子支气管镜联合TBLB、TBNA、BAL及BB等检查多种取材方法对ILD的诊断具有重要价值。Objective To estimate the diagnostic value of electronic bronchoscopy and different biopsy modalities in diffuse interstitial lung diseases（ILD）.Methods 129 patients with ILD,who were negative sputum smears for tubercle bacilli and pathological examination for tumor,were received electronic bronchoscopy,transbronchial biopsy （TBLB）,transbronchial needle aspiration （TBNA）,brushing and bronchoalveodar lavage （BAL）,brochial brushing （BB）.Results There were 64 cases of idiopathic pulmonary fibrosis （49.6%）,13 of secondary pulmonary fibrosis （10.1 %）,17 of lung cancer （13.2%）,7 of pulmonary tuberculosis （5.4%） and other rare pulmonary diseases were diagnosed by above mentioned methods.There were 18 of 129 cases （14%） which could not be diagnosed by electronic bronchoscopy;Electronic bronchoscopy and different biopsy modalities is more effective than TBLB in diagnosis （P0.05）.Conclusion Electronic bronchoscopy,together with TBLB,TBNA,BAL and BB plays a key role in the diagnosis of ILD.

关 键 词：弥漫性肺间质性疾病 电子支气管镜检查 诊断 

分 类 号：R443[医药卫生—诊断学] R563.9[医药卫生—临床医学]