动态脉压与高血压患者靶器官损害的关系  

Relation Between the Dynamic Pulse Pressure and Target Organ Damage in Patients With Hypertension

作　　者：石桂良[1] 邓新桃[1] 赵建祥[1] 郑金国[1] 

机构地区：[1]扬州大学医学院附属兴化人民医院,兴化225700

出　　处：《内科急危重症杂志》2010年第5期244-245,共2页Journal of Critical Care In Internal Medicine

摘　　要：目的:探讨动态脉压与高血压靶器官损害之间的关系。方法:将221例高血压患者按脉压值分为A、B、C组,对患者的一般资料及超声心动图测量的左心室射血分数、肾功能进行统计学分析比较。结果:不同脉压组在病程和血低密度脂蛋白水平间存在显著性差异(P<0.01),随着脉压的增加,高血压病患者的舒张期二尖瓣口血流频谱A峰与E峰峰值流速比(PVA/PVE)、室间隔厚度(IVSTd)、左心室后壁厚度(LVPWTd)、尿微量白蛋白(Um-Alb)均增加,肌酐清除率(Ccr)下降。结论:高血压患者脉压增宽与靶器官的损害密切相关。Objective：To study the relation between the dynamic pulse pressure and target organ damage in patients with hypertension.Methods：Two hundred and twenty-one cases with hypertension were divided into group A,group B and group C according to pulse pressure values.General data,left ventricular ejection fraction and renal function were statistically analyzed and compared.Results：The course of the disease and low density lipoprotein were significant difference among different pulse pressure group （P0.01）.Along with the increased pulse pressure in patients with hypertension,diastolic mitral inflow A peak and E peak of spectrum peak velocity ratio （PVA/PVE）,interventricular septum thickness （IVSTd）,left ventricular posterior wall thickness （LVPWTd）,urinary albumin （UmAlb） were increased,creatinine clearance rate （Ccr） was decreased.Conclusion：Widened pulse pressure is closely related to target organ damage.

关 键 词：高血压病 动态脉压 左心室功能 肾功能 

分 类 号：R544.1[医药卫生—心血管疾病]