生山药及麸炒山药的质量标准研究  

Study on quality standard of Rhizoma Diosoreae and Rhizoma Diosoreae stir-baked with bran

作　　者：杨连菊[1] 冯学锋[1] 杨京玉[1] 张淑运[1] 贾芳芳[1] 格小光[1] 

机构地区：[1]中国中医科学院中药研究所,北京100700

出　　处：《中国中药杂志》2010年第21期2846-2849,共4页China Journal of Chinese Materia Medica

摘　　要：目的:补充完善生山药及麸炒山药的质量标准,为提高2种饮片的现行标准提供实验数据。方法:收集4个产地9批次的生山药及麸炒山药,分别进行鉴别、水分、总灰分、酸不溶性灰分、重金属、农药残留、微生物、浸出物、含量测定的实验研究。结果:生山药及麸炒山药的薄层鉴别特征明显,专属性强。增加了二者酸不溶灰分限度要求,分别不得过0.5%,0.3%。增加了5种重金属及有害元素、2种有机氯农药残留和3种微生物的限量要求;其中铅均不得过2×10-7,镉均不得过2×10-7,铜均不得过1×105,砷均不得过3×10-7,汞均不得过1×10-7;六氯化苯(BHC)均不得过1×10-7;双对氯苯基三氯乙烷(DDT)均不得过1×10-7;菌落总数分别不得低于2 000,600 cfu.mL-1;大肠菌数均不得过<30 MPN.100 g-1;均不得检出霉菌。增加了含量测定项,尿囊素含量均不得低于0.15%。结论:本研究系统,数据准确,方法稳定简单,可作为提高2010年版《中国药典》中生山药、麸炒山药质量控制标准的科学依据。Objective： To perfect the current standard of Rhizoma Diosoreae and Rhizoma Diosoreae stir-baked with bran by improving quality standards of the two processed pieces.Method： The quality standards were established according to 9 batches of processed pieces,separately.The standards contains items of identification,water,total ash,acid-insoluble ash,extractives,heavy metals limit,organochlorine limit,microbial limit and assay.Result： The TLC of the two pieces was characteristed.The contents of acid-insoluble ash in the two pieces were increased,not more than 0.5%,0.3%,respectively.The content limits of five kinds of heavy metals and harmful elements,two kinds of residual organochlorine pesticides and three microbial limits were increased.There were no more than 2×10^-7 of lead,2×10^-7 of cadmium,1×10^-5 of copper,3×10^-7 of arsenic,1×10^-7 of mercury,1×10^-7 of hexachlorocyclohexane（BHC） and 1×10^-7 of chlorophenothane（DDT）in the two processed pieces,respectively.There were no more than 2 000 and 600 cfu·mL-1 in the two pieces,respectively and no more than 30 MPN·100 g-1 and fungi can not be tested in the two pieces.The contents of allantoin in the two pieces were no more than 0.15%.Conclusion： This method is simple and suitable for the quality control of the two processed pieces.

关 键 词：麸炒山药 质量标准 尿囊素 

分 类 号：R282[医药卫生—中药学]