清热活血方治疗冠心病急性心肌梗死60例临床观察  

Effect of Qingre Huoxue Recipe on the 60 Coronary Heart Disease Patients with Acute Myocardial Infarction

作　　者：吴伟[1] 彭锐[1] 李荣[1] 吴辉[1] 黄衍寿[1] 

机构地区：[1]广州中医药大学第一附属医院心内科,广东省广州市机场路16号510405

出　　处：《中医杂志》2010年第10期905-908,共4页Journal of Traditional Chinese Medicine

摘　　要：目的观察清热活血方对冠心病急性心肌梗死患者的短期临床疗效及安全性。方法 60例冠心病急性心肌梗死患者随机分为治疗组和对照组各30例,对照组给予常规西医治疗,治疗组给予常规西医治疗加清热活血方,每天1剂,疗程均为30天,疗程结束时比较两组证候积分、C-反应蛋白(CRP)、白细胞总数(WBC)、中性粒细胞百分比(NEU)、心率、血压、不良事件发生率、1个月及6个月随访终点事件发生率等指标。结果两组患者治疗前后证候积分、CRP水平、WBC及NEU变化差异有统计学意义(P<0.05或P<0.01)。结论清热活血方治疗急性心肌梗死在临床证候积分改善及体内炎症因子水平的下降方面均具有明显的疗效,且安全性良好。Objective To investigate the short term effect and safety of Qingre Huoxue Recipe （Recipe for clearing heat and activating blood） on the coronary heart disease patients with acute myocardial infarction. Methods Sixty patients were randomized into treatment group and control group. The former received a routine western medicine treatment plus Qingre Huoxue Recipe,one dose per day,while the latter received a routine western medicine treatment only,for a course of 30 days. After the treatment was finished,symptom score,C-reactive protein （CRP）,white blood cells （WBC） count,neutrophil （NEU） percentage,heart rate,blood pressure,incidence of adverse events,and incidence of endpoint events at the end of 1-month and 6-month follow-up were compared between groups. Results There existed a significant statistical difference in the symptom scores,CRP level,WBC count,and NEU percentage in the two groups before and after treatment （P〈0.05 or P〈0.01）. Conclusion Qingre Huoxue Recipe is good and safe in improving the score of heat syndromes and lowering the inflammatory factors in the short term treatment of acute myocardial infarction of coronary heart disease patients.

关 键 词：清热活血方 冠心病 急性心肌梗死 

分 类 号：R259[医药卫生—中西医结合]