肌钙蛋白Ⅰ(cTnI)、钠尿肽(BNP)在急性心肌梗死早期诊断中的应用探讨  

Discussion on the Values of cTnI and BNP in Early Diagnosis of Acute Myocardial Infarction

作　　者：李福坤[1] 王刚[1] 朱一堂[1] 张瑞青[1] 马晓博[1] 

机构地区：[1]河北省沧州市中心医院检验科,沧州061001

出　　处：《中国医药导刊》2010年第10期1767-1768,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨肌钙蛋白I(cTnI)、钠尿肽(BNP)联合诊断在早期急性心肌梗死(AMI)诊断中的作用。方法:收集胸痛发作时间在3小时以内的急诊患者120例,按AMI诊断标准分为急性心肌梗死组(AMI组)和非急性心肌梗死组,比较两组间血清BNP和cTnI水平及联合检测与单独检测的敏感性和特异度。结果:两组间血清BNP和cTnI水平,AMI组明显高于非AMI组,联合检测的敏感性和特异度均高于单独检测。结论:AMI患者在发病3小时内血清cTnI及BNP水平明显升高且联合检测有助于AMI的早期诊断。Objective：To evaluate the values of plasma brain natriuretic peptide（BNP） and Troponin I （cTnI）in early diagnosis of acute myocardial infarction.Methods：120 emergency cases with chest pain less than 3 hours divided into AMI group and non-AMI group,then compared the levels of plasma BNP and cTnl in two groups.Results：The plasma BNP and cTnI concentration in AMI group was obviously higher than non-AMI group.Conclusion：The levels of plasma BNP and cTnI are increased obviously in patients with AMl,which has chest pain less than 3 hours,and BNP and cTnI can be surrogate markers for early diagnosis of acute myocardial infarction.Sensitivity and specificity in early diagnosis of acute myocardial infarction using BNP and cTnl together are higher than using single marker.

关 键 词：急性心肌梗死 肌钙蛋白I 钠尿肽 

分 类 号：R542.22[医药卫生—心血管疾病]