双黄连注射液与10%葡萄糖注射液配伍研究  

Study on combination of Shuanghuanglian Injection and 10% Glucose Injection

作　　者：刘蕊莉[1] 高春联[1] 马瑞娟[1] 苗明三[1] 

机构地区：[1]河南中医学院,河南郑州450008

出　　处：《中医学报》2010年第6期1145-1146,共2页Acta Chinese Medicine

基　　金：河南省自然科学基金项目(编号:0411041900);郑州市科技领军人才(编号:0910SGYS3527)

摘　　要：目的:探讨双黄连注射液与10%葡萄糖注射液的适宜配伍浓度。方法:用10mL、20mL、25mL、30mL及35mL双黄连注射液,分别与200mL10%葡萄糖注射液配伍,观察其在4h内微粒变化,在4h内的pH值、紫外吸收的变化。结果:20mL及以下配伍液放置4h以内,微粒符合药典规定,pH值无明显变化;25mL及以上配伍液微粒不符合药典规定。结论:20mL及以下双黄连注射液与10%葡萄糖注射液配伍在4h内可以应用。：Objective ：To study the Appropriate concentration compatibility of shuanghuanglian Injection mixed with 10% Glucose Injection in clinical application. Methods： 200 ml 10% Glucose Injection mixed with 10 ml,20 ml,25 ml,30 ml,35 ml shuanghuanglian Injection separately, observing the change of appearance, particles 4h after mixing, the change of PH value, UV absorption 4 h after mixing. Results： No significant change was noted in appearance, PH value and the particles were meet the pharmacopoeia in the mix- ture 20ml and the below within 4 h after mixing; the particles did not meet the pharmacopoeia in the mixture 25 ml and the above. Conclusion： Shuanghuanglian Injection and 10% Glucose Injection could be mixed to use in 25 ml the below within 4 h.

关 键 词：双黄连注射液 10%葡萄糖注射液 配伍浓度 微粒 

分 类 号：R284.1[医药卫生—中药学]