冰片的药理作用及其机制研究进展  

Research advance in pharmacological effect of borneol and the underlying mechanism

作　　者：魏楚蓉[1,2] 伍赶球[1] 

机构地区：[1]中南大学湘雅医学院组织学与胚胎学系,长沙410013 [2]井冈山大学医学院生理教研室,江西吉安343000

出　　处：《国际病理科学与临床杂志》2010年第5期447-451,共5页Journal of International Pathology and Clinical Medicine

摘　　要：冰片是中医药中一味常用佐药。中医认为其有开窍醒神、清热止痛、生肌之效。现代医学研究表明冰片有抗炎镇痛、抗菌、抗病毒、保护心脑、双向调节神经系统、提高其他药物生物利用等作用。此外,冰片在肿瘤的治疗中可能也起到一定作用。而这些作用可能是冰片通过提高生物膜屏障通透性、影响肾上腺素、五羟色胺、一氧化氮、钙离子等物质的含量等一系列机制而实现。As one of commonly used adjuvant,borneol has been considered to have a therapeutic effect for waking up a patient from unconsciousness,expelling heat to alleviate pain and promoting granulation.It has been shown that borneol has effects of anti-inflammatory,analgesia,antibiosis,antivirus,protection of heart and brain,regulation of nervous system in two-ways,boost of other drug bioavailability,etc.In addition,borneol may have role in cancer prevention.These effects of borneol is related to increasing the biomembrane permeability and changing the contents of adnephrin,serotonin,NO and Ca2＋.

关 键 词：冰片 药理作用 机制 生物利用度 

分 类 号：R285[医药卫生—中药学]