女性生殖道沙眼衣原体感染免疫病理机制研究现状  

Immunopathogenesis Research of Chlamydia Trachomatis Infection in Female Reproductive Tract

作　　者：付文静[1] 郭光红[2] 付爱峰[3] 张建明[1] 张静[3] 

机构地区：[1]滨州医学院附属医院皮肤性病科,山东滨州256603 [2]滨州医学院附属医院妇科,山东滨州256603 [3]滨州医学院附属医院产科,山东滨州256603

出　　处：《中国皮肤性病学杂志》2010年第11期1061-1063,共3页The Chinese Journal of Dermatovenereology

摘　　要：女性生殖道沙眼衣原体(CT)感染可导致宫颈炎、盆腔炎、慢性盆腔痛、不孕、异位妊娠等一系列严重疾病及并发症,业已成为全球备受关注的公共卫生问题之一。目前观点认为,感染相关免疫病理损伤为其主要致病机制。本文将从固有免疫与获得性免疫两方面对女性生殖道CT感染免疫病理机制研究现状作一综述。Sexually transmitted ehlamydia trachomatis infection is among the most important global publie health concern with major burden on female genital tract because of induction of cervicitis, pelvic inflammatory disease （PID） which often lead to severe clinical sequelae such as chronic pelvic pain, infertility and ectopic preg- nancy（EP）. Today infection related immunological injury has been mostly recommended as the key pathogenesis. This article will review the current views on the immunopathogenesis in respects of innate and adaptive immune responses to chlamydial infection in female reproductive tract.

关 键 词：沙眼衣原体 免疫病理机制 女性生殖道 热休克蛋白 细胞因子 

分 类 号：R374.1[医药卫生—病原生物学]