基于环糊精和富勒烯偶联体系的新型分子机器  

Novel Molecular Machine Based on the Cyclodextrin-Fullerene Coupling System

作　　者：孙涛[1] 张华承[1] 李月明[1] 辛飞飞[1] 孔丽[1] 郝爱友[1] 

机构地区：[1]山东大学化学与化工学院,济南250100

出　　处：《化学进展》2010年第11期2156-2164,共9页Progress in Chemistry

基　　金：山东大学研究生自主创新基金项目(No.yzc09056)资助

摘　　要：超分子化学是当前热点研究领域之一。利用超分子体系来模拟宏观过程,进而将宏观机器纳米尺寸化更是备受瞩目。环糊精与富勒烯各自具有非常优良的性质,而基于环糊精和富勒烯偶联体系的新型"加工型"分子机器,与传统的"运动型"分子机器不同,不是强调分子间与分子内的位置变化,而是强调对特定客体分子"识别-捕捉-加工-释放"的过程。这种新型的分子机器将为包括生物酶模拟、生物过程研究、光能固定等领域的研究提供新思路。本文综述了环糊精和富勒烯偶联体系的研究进展。首先介绍了不同种类的环糊精和富勒烯偶联体系的合成,包括合成思路、步骤方法及表征;然后叙述了此体系的应用领域,包括分子识别、DNA裂解、电子传输等方面;最后结合现阶段的研究状况,对其发展前景进行了展望。Supramolecular chemistry is a hot research topic in current chemistry.It is more attractive to build machines in a nanometer scale by mimicking the macro-scale processes through supramolecular way.Being different from the traditional ＂motile ＂ molecular machines,the novel ＂processing ＂ molecular machines based on the cyclodextrin-fullerene coupling system focus on a ＂recognition-capture-processing-release＂procedure,but not on the position changes in and between molecules.This new molecular machine will supply a new approach in the area of enzyme mimic,biological process research,photo-immobilization,etc.Here,the development of cyclodextrinfullerene coupling system is reviewed.Firstly,the synthesis of different kinds of cyclodextrin-fullerene coupling systems,including the synthesis clues,approaches and characterization,is introduced.Then,the application of the system is emphatically described,including molecular recognition,DNA cleavage and electron transfer,etc.Finally,based on current developments of the system,the prospects are pointed out.

关 键 词：环糊精 富勒烯 偶联体系 分子机器 

分 类 号：O621.3[理学—有机化学] O641.3[理学—化学]