重度子痫前期孕妇血清和胎盘组织中脂质代谢的研究  

The study of lipid in serum and placenta with preeclampsia pregnancy

作　　者：尹雅莉[1] 程淑清[2] 

机构地区：[1]中国辐射防护研究院附属医院妇产科,太原030006 [2]宁波市妇女儿童医院妇产科

出　　处：《中国优生与遗传杂志》2010年第11期68-69,35,F0004,共4页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨脂质代谢在子痫前期发病中的作用。方法回顾性分析310例重度子痫前期孕妇(子痫前期组)和300例健康晚孕妇女(正常妊娠组)的血脂水平;酶法检测26例子痫前期组和30例正常妊娠组血脂浓度;油红染色法检测12例子痫前期组和12例正常妊娠组胎盘组织中脂质水平。结果子痫前期组血脂水平明显高于正常妊娠组;子痫前期组胎盘组织较正常妊娠组有明显脂质沉积。结论子痫前期存在显著的高血脂异常代谢。脂质代谢可能在子痫前期发病中起着一定的作用。Objective：To discuss the effectiveness of lipid in the pathogenesis of preeclampsia.Methods：To retrospectively explore lipid /lipoprotein profile of 310 cases of severe preeclampsia and 300 normal pregnant women.The lipids levels of serum with 26 cases of severe preeclampsia and 30 normal pregnant women were detected by enzymid method.The lipids levels of placenta with 12 cases of severe preeclampsia and 12 normal pregnant women were analyzed by oil red staining.Results：The levels of serum lipids were increased significantly,and lipids were generally deposited in placenta in preeclampsia women.Conclusion：The abnormal metabolism of hyperlipermia were found significantly in preeclampsia.Lipid possibly has a significant role in the pathogenesis of the preeclampsia.

关 键 词：子痫前期 血脂 胎盘组织 

分 类 号：R714.245[医药卫生—妇产科学]