CDPI在肾移植术后急性排异反应中的临床意义  

THE CLINICAL SIGNIFICANCE OF CDPI IN ACUTE REJECTION AFTER RENAL TRANSPLANTATION

作　　者：杨敏[1] 赵劲涛[1] 张庶[2] 孙琰[2] 

机构地区：[1]昆明医学院第二附属医院肾脏科,昆明650101 [2]昆明医学院第二附属医院超声诊断科

出　　处：《现代预防医学》2010年第22期4366-4367,共2页Modern Preventive Medicine

摘　　要：[目的]探讨超声CDPI技术在肾移植术后急性排异反应中的临床意义。[方法]正常肾脏组和肾移植术后组,采用彩色多普勒超声诊断仪,带有CDPI技术功能,对移植肾和正常肾脏进行扫查,观察肾脏的大小、形态、皮髓分界,对比分析移植肾和正常肾实质血流灌注情况以及移植肾急性排异反应期和治疗后肾实质血流灌注的情况、血管阻力指数等参数。[结果]正常肾脏组,肾脏血流丰富,CDPI:从主肾动脉至弓形动脉四级血管血流信号丰富、清晰,呈连续树枝状。脉冲多普勒测定各级肾动脉血流参数正常。移植肾组,(1)肾功能稳定期:移植肾大小正常或稍大,形态丰满,CDPI显示各级肾动脉血流信号丰富,呈连续树枝状,脉冲多普勒测定四级肾动脉血流指数正常。(2)急性排异期:移植肾明显肿大,CDPI显示肾实质血流信号稀少,主肾动脉和段动脉血流呈连续性,叶间动脉闪烁状,主肾动脉、段动脉血流速度减低,阻力指数增高,叶间动脉血流频普频普呈断续状,舒张期无血流信号,弓形动脉血流速度偏低。[结论]CDPI检查技术不仅对早期诊断肾移植后急性排异有很大的价值,同时对监测排异反应的治疗效果也有重要的临床意义。[Objective] To investigate the ultrasonic CDPI in acute rejection after renal transplantation in the clinical sig-nificance.[Methods] In the normal kidney group and renal transplantation group,color Doppler ultrasonography with CDPI technical function was used to scan the normal kidneys transplanted kidney,and observed the size,shape,skin marrow boundaries of the kidney.We compared the renal transplantation and normal renal perfusion,and acute renal allograft rejection and treatment of renal perfusion conditions,vascular resistance index and other parameters.[Results] In the normal kidney group,the renal blood flow rich,CDPI： from the main renal artery to the arcuate artery blood flow signals four rich,clear,and a continuous dendritic.We determined the renal artery Doppler blood flow parameters at all levels to normal.Graft group,（1） Stable renal function： normal or slightly larger graft size,shape fullness,CDPI showed renal artery blood flow at all levels of wealth,a continuous dendritic,and four renal artery pulsed Doppler flow index is normal.（2） Acute rejection： the trans-plant kidney was enlarged,CDPI showed a few of renal blood flow signals in real terms,and the main renal artery and segmen-tal artery blood flow was continuous,like flashing interlobar artery,the main renal artery,segmental artery blood flow velocity reduced,the resistance index increased,and blood flow between the frequency of leaf P P frequency was intermittent-like,no blood flowed in diastole,and the arcuate artery flow velocity was low.[Conclusion] CDPI examination techniques not only have great value in the early diagnosis of acute rejection after renal transplantation,while have great clinic value in the treat-ment of rejection.

关 键 词：肾移植术后 急性排异 超声 CDPI技术 

分 类 号：R617[医药卫生—外科学]