瑶药扁担藤化学成分的研究  

Chemical Constituents of Tetrastigma planicaule(Hook.) Gagnep.

作　　者：邵加春[1] 何翠红[1] 雷婷[1] 洪爱华[2] 岑颖洲[1] 

机构地区：[1]暨南大学化学系,广州510632 [2]暨南大学分析测试中心,广州510632

出　　处：《中国药学杂志》2010年第21期1615-1617,共3页Chinese Pharmaceutical Journal

基　　金：国家自然科学基金资助项目(20472024;20772047);广东省自然科学基金资助项目(039213)

摘　　要：目的研究我国瑶族植物药扁担藤[Tetrastigma planicaule（Hook.）Gagnep.]的化学成分。方法采用色谱技术进行分离,根据化合物的理化性质和光谱数据鉴定其结构。结果从扁担藤茎的体积分数95%乙醇提取物中分离得到8个化合物,分别鉴定为stigmast-4-en-6β-ol-3-one（1）,7α-hydroxysitosterol（2）,古柯二醇（3）,水杨酸（4）,香草酸（5）,丁香酸（6）,原儿茶酸（7）,glycerol-2-（3-methoxy-4-hydroxybenzoic acid）ether（8）。结论所有化合物均为首次从该植物中分离得到,其中化合物1~3,5~8为首次从该属植物中分得。化合物8为首次从天然产物中分离得到。OBJECTIVE To investigate the chemical constituents of Tetrastigma planicaule（Hook.） Gagnep as a medicinal plant of Yao nationality in China.METHODS Compounds were isolated by various column chromatography.Their structures were elucidated by physicochemical and spectral analysis.RESULTS Ten compounds were isolated from the 95% ethanol extract of the stems of Tetrastigma planicaule and their structures were identified as stigmast-4-en-6β-ol-3-one（1）,7α-hydroxysitosterol（2）,erythrodiol（3）,salicylic acid（4）,vanillic acid（5）,syringic acid（6）,protocatechuic acid（7） and glycerol-2-（3-methoxy-4-hydroxybenzoic acid） ether（8） respectively.CONCLUSION All these compounds were isolated from this plant for the first time,and compound 1-3,5-8 were firstly isolated from the genus Tetrastigma.Compound 10 was isolated from natural products for the first time.

关 键 词：扁担藤 化学成分 酚酸 

分 类 号：R284[医药卫生—中药学]