2型糖尿病肥胖患者的血脂水平与胰岛素抵抗的关系  

Association between Serum Lipid Profile and Insulin Resistance in Type 2 Diabetic Patients with Obesity

作　　者：倪黎刚[1] 刘俊恒[1] 潘继承[1] 

机构地区：[1]江苏省省级机关医院,江苏南京210024

出　　处：《临床医学工程》2010年第11期37-38,共2页Clinical Medicine & Engineering

摘　　要：目的探讨2型糖尿病且肥胖患者血脂水平异常与胰岛素抵抗的关系。方法选择66例确诊为2型糖尿病且符合肥胖标准的患者,对他们的血糖、血脂(包括TG、TC、HDL-C、LDL-C)、胰岛素抗体进行检测分析,并设定相应对照组。结果 2型糖尿病且肥胖组血糖、胰岛素、TG、TC、HDL-C、LDL-C、胰岛素抗体阳性率与正常对照组和正常肥胖组比较明显异常(P<0.01)。结论胰岛素抵抗(IR)与2型糖尿病患者肥胖和血脂异常有明显关联,改善IR,控制血脂水平,对预防2型糖尿病的发展以及控制并发症的发生有重要意义。Objective To study the association between dyslipidemia and insulin resistance in type 2 diabetic patients with obesity. Methods Serum TG, TC, HDL-C, LDL-C, Insulin antibody levels are determined in 66 T2DM patients with obesity and in control groups. Results The serum Glu, Insulin, TG, TC, LDL-C levels of T2DM patients with obesity were significantly higher than the levels of normal people （P 〈0.01）. The positive rates of insulin antibody in T2DM patients with obesity were also significantly higher than those of normal people（P〈0.01）. Conclusion There are certain relationships between dyslipidemia and insulin resistance in T2DM patients with obesity. It＇s important to improve insulin resistance and control dyslipidemia in T2DM patients with obesity.

关 键 词：2型糖尿病 肥胖 胰岛素抵抗 

分 类 号：R587.1[医药卫生—内分泌]