肺结核患者巨细胞病毒感染的检测及临床意义  

Tuberculosis patient cytomegalovirus infection and clinical significance

作　　者：陈廷[1] 聂尚丹[2] 赵建磊 李雷生[2] 杨海霞[2] 叶黎明[2] 

机构地区：[1]济宁医学院继续教育学院,山东济宁272067 [2]济宁医学院医学检验系,济宁272067 [3]胶州市卫生局,山东胶州266300

出　　处：《济宁医学院学报》2010年第5期329-331,共3页Journal of Jining Medical University

摘　　要：目的了解肺结核患者人巨细胞病毒(HCMV)的感染情况及可能对结核病情的影响。方法应用金标免疫斑点渗滤法检测HCMV-IgM抗体和HCMV-IgG抗体。结果 51例肺结核患者HCMV-IgM阳性数5例,阳性率9.80(;HCMV-IgG阳性数20例,阳性率为39.22(;肺结核患者HCMV抗体阳性率与对照组比较,差异无统计学意义(P>0.05);HCMV感染可能导致病毒性肺炎,造成结核菌的扩散。结论肺结核患者可导致HCMV活动性感染,并可能造成结核病情的复杂化。Objective To understand Tuberculosis human cytomegalovirus（HCMV） infection and its possible impact on the TB situation.Methods Immune gold dot filtration assay was used to detect HCMV-IgM antibodies and HCMV-IgG antibody.Results The number of 51 cases HCMV-IgM positive patients with tuberculosis is 5,the positive rate is 9.80%;HCMV-IgG positive number is 20,the positive rate is 39.22%;HCMV antibody positive rate in TB patients was compared with control group,and the difference was not statistically significant（P0.05）;HCMV infection may lead to viral pneumonia and cause the spread of TB.Conclusion The patients with tuberculosis can lead to HCMV active infection,and may cause the complicated situation of tuberculosis.

关 键 词：肺结核 巨细胞病毒感染 金标免疫法 抗体 

分 类 号：R521[医药卫生—内科学]