常规剂量氨茶碱对中老年人运动能力和氧耗量的影响  

Influence of aminophylline in general dosage on exercise performance in middle aged and aged subjects

作　　者：周彩存[1] 王爱华[1] 刘玉珠 

机构地区：[1]蚌埠医学院附属医院肺科

出　　处：《蚌埠医学院学报》1999年第2期77-78,共2页Journal of Bengbu Medical College

摘　　要：目的：探讨静脉注射常规剂量氨茶碱对正常中老年人运动肺功能的影响。方法：１４例正常中老年人分别于静脉注射０．２５ｇ氨茶碱前后，作症状限制性运动肺功能检查。运动负荷递增采用斜坡法，每分钟增加１０Ｗ。电脑自动连续记录被检者静息与运动时的呼吸参数、运动负荷、血氧饱和度及心率等。结果：氨茶碱能显著增加静息时分时通气量、呼吸频率及心率，但对运动能力和最大运动负荷时的分时通气量、氧耗量和通气方式等均不产生明显的影响。Objective:To investigate effects of aminophylline in general dosage on exercise performance in normal middle aged and aged subjects.Methods:Symptom limited exercise tests were taken in 14 normal middle aged and aged persons before and after intravenous injection of 0.25 g aminophylline.Exercise workload was set to be increased in ramp of 10 watts per minute.Respiratory parameters,exercise workload,oxygen saturation and heart rate etc.were measured during rest and exercise.Results:Aminophylline significantly increased minute ventilation,breath frequency and heart rate during rest,but did not affect exercise performance and minute ventilation,oxygen consumption and respiratory patterns etc.at the maximal exercise workload.Conclusions:Intravenous injection of general dosage aminophylline does not influence exercise performance and oxygen consumption in normal middle aged and aged persons.

关 键 词：氨茶碱 运动试验 中老年人 氧耗量 肺功能 

分 类 号：R974.3[医药卫生—药品] R443.6[医药卫生—药学]