阿奇霉素乳膏的制备及质量控制  

Preparation and Quality Control of Azithromycin Cream

作　　者：傅晓琴[1] 刘祖雄[2] 王志朝[2] 

机构地区：[1]武汉亚洲心脏病医院药剂科,湖北武汉430022 [2]中国人民解放军广州军区武汉总医院药剂科,湖北武汉430070

出　　处：《中国药业》2010年第21期38-39,共2页China Pharmaceuticals

摘　　要：目的介绍阿奇霉素乳膏的制备及质量控制方法。方法以阿奇霉素为原料制备阿奇霉素乳膏,采用二剂量法进行含量测定及稳定性考察。结果制剂中主药阿奇霉素平均回收率为99.88%,RSD为0.28%。结论该制剂制备工艺简单、性质稳定,适用于医院制剂室配制和临床使用。Objective To introduce the preparation and quality control method of Azithromycin Cream.Methods To prepare Azithromycin Cream with azithromycin raw material.The content of azithromycin was measured by two-dosage method and its stability was observed.Results The average recovery rate of azithromycin was 99.88%,RSD was 0.28%.Conclusion This method is simple and the quality of products is stable.The products is suitable for hospital preparation and application in clinic.

关 键 词：阿奇霉素 乳膏 稳定性 

分 类 号：R944.21[医药卫生—药剂学] R986[医药卫生—药学]