精子功能相关精浆蛋白质的蛋白组学研究进展  

Progress in Proteomics Assessment of Seminal Plasma Proteins with Emphasis on the Spermatozoa Function

作　　者：李鸿岩[1] 赵兴绪[2] 张勇[2] 杨永新[2] 徐铁山[2] 

机构地区：[1]甘肃农业大学生命科学技术学院,兰州730070 [2]甘肃农业大学动物医学院,兰州730070

出　　处：《中国畜牧兽医》2010年第11期110-114,共5页China Animal Husbandry & Veterinary Medicine

基　　金：甘肃省"十五"科技攻关计划项目(2GS035-A41-001)

摘　　要：精浆蛋白质对生殖过程中的精子功能有显著影响,包括顶体反应、精子获能、精子贮存、精子竞争和受精。精浆蛋白质的研究已有很长的历史,而且牛精浆蛋白、热休克蛋白、富含半胱氨酸分泌蛋白等几种主要的精浆蛋白质已被成功分离鉴定。蛋白质组学研究方法和技术的迅速发展,为全面解析精浆蛋白质组提供了新的研究策略,提高了研究者探索精浆蛋白质未知领域的效率。作者综述了精子功能相关精浆蛋白质研究的相关信息及近年来精浆蛋白质组的研究进展,从蛋白质水平上阐述了精浆蛋白质与精子获能、贮存及受精等功能的关系。Seminal plasma proteins show striking effects on spermatozoa function in a variety of reproductive processes,including acrosome reaction,sperm capacitation,sperm storage,competition,and fertilization.Seminal plasma proteins were isolated and identified for a long history,several of major seminal plasma proteins have been identified,such as bovine seminal protein,heat shock protein,cystein-rich secretory protein.Proteome is applied successfully in seminal plasma proteins research,has given to new research strategies and improved the efficiency of researchers in exploring the unknown field of seminal plasma.This review introduced some essential information about seminal plasma proteins associated with spermatozoa function and progress in seminal plasma proteome,and provides valuable information to clarify the relationship between seminal plasma proteins and sperm capacitation,sperm storage,and fertilization function at the protein level.

关 键 词：精浆蛋白质 精子功能 蛋白质组 

分 类 号：S828[农业科学—畜牧学]