硝苯地平舌下含服致老年高血压急症患者低血压  

Hypotension caused by sublingual nifedipine in an elderly patient with hypertensive emergency

作　　者：周长甫[1] 张爱香[1] 閤玲莉[1] 

机构地区：[1]湖北省军区元宝山干休所卫生所,武汉430079

出　　处：《药物不良反应杂志》2010年第5期369-370,共2页Adverse Drug Reactions Journal

摘　　要：1例82岁女性患者,因高血压急症给予舌下含服硝苯地平10mg。20min后患者出现乏力,心慌,四肢冰冷、面色苍白。BP80/50mmHg,P110次/min。心电图检查示窦性心动过速。给予扩充血容量、心电监护及其他对症支持治疗。20min后BP120/70mmHg,乏力、心慌等不适感逐渐缓解。次日,患者血压再次升高,再次给予舌下含服硝苯地平,上述症状再次出现,经对症治疗后好转。A 82-year-old woman with hypertensive emergency received sublingual nifedipine 10 mg.Twenty minutes later,the patient presented with asthenia,palpitation,coldness in her extremities,and facial pallor.Her blood pressure was 80/50 mm Hg and pulse rate was 110 beats/min.Electrocardiogram showed sinus tachycardia.She was given blood volume expansion,ECG monitoring,and other supportive and symptomatic treatment.Twenty minutes later,her blood pressure was 120/70 mm Hg and her discomfort including asthenia and palpitation gradually improved.The next day,her blood pressure was elevated again.The above-mentioned symptoms recurred after administration of sublingual nifedipine and improved after symptomatic therapy.

关 键 词：硝苯地平 不良反应 低血压 

分 类 号：R544.1[医药卫生—心血管疾病]