核素心肌灌注显像在疑似冠心病的糖尿病患者中的临床应用  

The clinical annlication of myocardial perfusion imaging in diagnosing patients with 2 type diabetes and a suspected coronary artery disease

作　　者：邓惠兴[1] 马爱群[2] 杨爱民[1] 程虎[1] 冉宏德[1] 

机构地区：[1]西安交通大学医学院第一附属医院核医学科,西安710061 [2]西安交通大学医学院第一附属医院心血管内科,西安710061

出　　处：《中国糖尿病杂志》2010年第11期834-837,共4页Chinese Journal of Diabetes

摘　　要：目的探讨^(99)Tc^m-MIBI心肌灌注显像在疑似冠心病的糖尿病患者中的应用价值。方法 95例2型糖尿病患者,其中接受^(99)Tc^m-MIBI运动负荷-静态心肌灌注显像35例,接受腺苷负荷-静态显像43例,仅作静息态17例。结果 (1)运动负荷、腺苷负荷、单纯静息显像三组阳性检出率为54.29%、53.48%和23.53%,负荷与静息态显像组间有统计学差异(P<0.05);(2)男、女患者组检出率分别为63.04%和28.13%(P<0.01);(3)42例心肌灌注显像提示心肌缺血患者中共检测灌注减低节段91段,单只、两支及三支血管病变的比例分别为55.81%、37.21%和6.98%;(4)检出心肌梗死4例,占4.21%。结论核素心肌灌注显像作为无创性的影像诊断技术,其规范使用对疑似冠心病的糖尿病患者早期诊断心肌缺血有重要应用价值。Objective To study the clinical value of Tc 99m-methoxyisobutylisonitrile （MIBI） myocardial perfusion imaging in patients with type 2 diabetes and a suspected coronary artery diseases. Methods 95 hospitalized patients were selected. Tc 99m-MIBI myocadical perfusion imaging were performed in all patients. Exercise stress test were received by 35 cases. Adenosine stress test were received by 43 cases. Rest imaging were received by 17 cases. Results The rate of abnormal findings in the three groups were 54. 29% ,53.48% and 23.53% respectively. Statistic difference were seen between stress groups and rest group （P〈0.05）, The rate of abnormalities in male and female group were 63.04% and 28. 13% respectively （P〈0.01）. 91 segments of perfusion abnormality were detected in 42 positive patients. The rates of single, two and multi vessel abnormality were 55.81%, 37.21% and 6.98% respectively. Myocardial infarction were found in 4 cases. Conclusions As a non invasive method, stress-rest Tc-99m-MIBI myocardial perfusion imaging plays an important role in diagnosis of coronary ischemia in patients with type 2 diabetes and a suspected coronary artery disease.

关 键 词：断层摄影术 甲氧某异丁基异腈 冠状动脉疾病 糖尿病 2型 

分 类 号：R587.1[医药卫生—内分泌]