自拟消癜冲剂辅助治疗过敏性紫癜  

Erythema Elimination Electuary Clinical Study as Adjuvant Therapy to Treat Anaphylactoid Purpura

作　　者：何胜尧[1] 吴仙娜[1] 蔡新民[2] 麦柳冰[1] 蔡小青[3] 徐俊鸿[4] 梁刚文[4] 李秀兰[1] 

机构地区：[1]广州中医药大学附属顺德中医院儿科,广东佛山528333 [2]广州中医药大学附属顺德中医院皮肤科,广东佛山528333 [3]广州中医药大学附属顺德中医院风湿科,广东佛山528333 [4]广州中医药大学附属顺德中医院制剂科,广东佛山528333

出　　处：《中国实验方剂学杂志》2010年第16期182-184,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：广东省中医药管理局立项课题(2007422)

摘　　要：目的:观察中西医结合治疗过敏性紫癜的临床疗效及初步探讨活血祛瘀法治疗HSP的作用机理。方法:60例过敏性紫癜的患儿随机分2组:中西医结合组(31例)和西医组(29例)。中西医结合组治疗上在传统西医治疗基础上加用"消癜汤",西医组则以西医治疗,不加用任何中药治疗。共观察24周,对比2组治疗前后症状、凝血功能、血小板计数等。结果:治疗组治愈率94%优于对照组62%(P<0.01),在降低纤维蛋白原水平及血小板数量上治疗组优于对照组(P<0.05)。结论:自拟消癜冲剂结合西医治疗能明显地改善过敏性紫癜的临床症状和部分凝血指标,且安全,值得推广。Objective：To observe the clinical effects using Chinese and western integrative medicine to treat anaphylactoid purpura.Method： 60 patients were randomly divided into two groups.Treatment group（use Chinese and western integrative medicine） and control group（only use Western medicine）.Compare and analyze the curative effect,symptoms,clotting function and other index of the two groups after 24 weeks.Result：Cure rate of treatment group（94%） is much better than the control group（62%）（P 〈 0.01）.And treatment group has lower fibrinogen levels and platelet counts than the control group（P 〈 0.05）.Conclusion：Using erythema elimination electuary and western medicine can significantly improve the clinical symptoms of anaphylactoid purpura and parts of coagulation parameters,worthy for promotion.

关 键 词：过敏性紫癜 中西医结合 高凝状态 

分 类 号：R285.6[医药卫生—中药学]