夜香树提取物对荷瘤小鼠免疫功能的影响  

Influence of Extract from Cestrum cocturnum on Immune Function of Tumor-bearing Mouse

作　　者：黄燕[1] 李鹏 罗雪菲[3] 王璐瑶[3] 吕金燕[3] 韦勇汉[3] 陆盛胜[3] 赖进科[3] 李淑[3] 钟振国[3] 

机构地区：[1]广西中医学院微生物免疫学教研室,南宁530001 [2]韶关医学院,广东韶关512005 [3]广西中医学院新药研究开发中心,南宁530001

出　　处：《中国实验方剂学杂志》2010年第15期114-116,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：广西科技厅基金项目(桂科能05112001-3A1)

摘　　要：目的:观察夜香树提取物对荷瘤小鼠免疫功能的调节作用。方法:通过检测H22荷瘤小鼠碳粒廓清率、血清溶血素水平、白细胞介素-2(IL-2)和肿瘤坏死因子α(TNF-α)含量变化,观察夜香树95%乙醇提取物175,350,700 mg.kg-1 ig对荷瘤小鼠免疫功能的影响。结果:夜香树提取物可明显提高H22荷瘤小鼠廓清指数和吞噬指数,并能显著提高血清中IL-2和TNF-α的含量(P﹤0.05),但对血清溶血素水平影响不明显。结论:夜香树提取物可增强荷瘤小鼠细胞免疫功能。Objective：To study the effect of the extract from Cestrum cocturnum on the immune function for the tumor-bearing mouse.Method：The routine methods were used to observed the carbon partical clearance,seurm hemolysin level,the contents of proteinic factor IL-2 and TNF-α of the H22 tumor-bearing mouse.Result：The high and middle dose of the extract from C.cocturnum could promote the carbon partical clearance speed and the content of the IL-2 and TNF-α.But the C.cocturnum had no obvious influence on the serum hemolysin level in the tumorbearing mouse.Conclusion：The extract from C.cocturnum could promote the cellular immune function of tumorbearing mouse.

关 键 词：夜香树提取物 荷瘤小鼠 免疫功能 

分 类 号：R285.5[医药卫生—中药学]