35例老年患者医院感染败血症临床分析  

Clinical Analysis of 35 Elderly Sepsis Patients Caused by Nosocomial Infection

作　　者：刘梅[1] 张军学[1] 张文娟[1] 刘建琴[1] 那薇[1] 

机构地区：[1]解放军306医院军休地干病房,北京100101

出　　处：《中华医院感染学杂志》2010年第22期3478-3479,共2页Chinese Journal of Nosocomiology

摘　　要：目的分析老年医院感染败血症患者的病原学特点与相关因素,制定防护对策。方法对2004年3月-2009年12月经血培养和临床资料证实的35例老年医院感染败血症患者的相关因素进行回顾性分析。结果 35例老年医院感染败血症患者共分离出病原菌35株,其中革兰阳性菌10株,占28.6%,革兰阴性菌22株,占62.8%,真菌3株,占8.6%;死亡率高达17.1%,老年医院感染败血症与老年患者基础疾病复杂严重、免疫力低下、中心静脉置入等侵入性诊疗护理操作、长期应用抗菌药物、环境及管理因素等密切相关。结论医护人员要全方位考虑老年患者发生医院感染的高危因素,合理用药,制定相关防护措施,以降低老年医院感染败血症的发生率与病死率。OBJECTIVE To analyze the pathogenic characteristic and related factors on 35 sepsis patients caused by nosocomial infection so that can establish the prevention measures. METHODS 35 elderly sepsis patients with nosocomial infection, verificated by blood culture and clinical data from Mar 2004 to Dec 2009, were retrospectively analyzed. RESULTS Totally 35 strains of Pathogenic bacteria were isolated among 35 elderly sepsis patients with nosocornial infection. 10 strains （28.6%） belonged to gram positive bacteria, 22 strains （62.9%） to gram-negative bacteria, and 3 strains to fungus. The mortality rate highly arrived at 17. 1%. The related factors including complicated basic diseases in the elderly patients, suppressed immunity, invasive method for medical diagnosis and therapy such as tube indwelling at central vein, long term treatment with antibiotics drugs, environmental and medical care factors, closly related with the elderly sepsis patients caused by nosocomial infection. CONCLUSIONS Medial staff should consider the high risk factors in elderly patients with nosocomial infection in a all round way. Rational antibiotics drugs should be chosen, and the related prevention measures should be made so as to decrease the morbidity and mortality of elderly sepsis patients caused by nosocomial infection.

关 键 词：老年患者 医院感染 败血症 

分 类 号：R515.3[医药卫生—内科学]