医院抗菌药物临床应用干预前后对比与分析  

Rational Usage of Antibiotics Pre-and Post-intervention in Our Hospital:Comparison and Analysis

作　　者：李静[1] 张永军[1] 朱晓庆[2] 彭曦[1] 智永刚[1] 

机构地区：[1]石河子大学医学院第一附属医院药剂科,新疆石河子832008 [2]石河子大学药学院,新疆石河子832000

出　　处：《中华医院感染学杂志》2010年第22期3560-3562,共3页Chinese Journal of Nosocomiology

基　　金：兵团科技攻关计划课题(医药专项2006GG54)

摘　　要：目的对比与分析干预前后医院抗菌药物合理使用状况,促进临床科学、合理用药。方法对医院干预前(2006年)和干预后(2008年)出院病历的抗菌药物使用情况进行统计、对比与分析。结果干预后,抗菌药物使用率下降了12.00%(P<0.01),抗菌药物合理使用率提高40.39%(P<0.01),Ⅰ类切口患者术后平均预防用药时间缩短了1.7d(P<0.01)。结论干预措施对促进医院抗菌药物的合理使用是可行和有效的。OBJECTIVE To compare and analyze the status of rational usage of antibiotics pre-and post-intervention, and to promote the development of scientific and rational clinical usage of antibacterial drugs. METHODS The data of medication of two patient groups in 2006 （pre-intervention） and 2008 （post-intervention） were collected and compared. RESULTS The prescription of antibiotics in the year 2008 was decreased by 12.00 % （P〈0.01） when compared with the year 2006. The rationality of antibiotics use was improved by 40. 39% （P〈0.01）, the average duration of antiseptic use on 1 incision operations was shortened by 1. 7 days （P〈0.01）. CONCLUSION The formulation and implementation of intervention methods of rational drug use in our hospital are proved practicable and effective.

关 键 词：抗菌药物 合理用药 干预 

分 类 号：R978.1[医药卫生—药品]