“氯-芬”合剂微泵法行小儿静脉麻醉的临床观察  

Clinical observation of“Ketamine fentanyl”mixture administered with micropump in pediatric intravenous anesthesia

作　　者：温汉新[1] 曹殿青[1] 姚华国[1] 陈书荣[1] 杨光平[1] 郝新光[1] 吴江[1] 

机构地区：[1]广东医学院附属医院

出　　处：《广东医学院学报》1999年第1期25-27,共3页Journal of Guangdong Medical College

摘　　要：目的：探讨“氯－芬”合剂微泵法行小儿静脉全麻的效果及其对患儿呼吸、循环的影响。方法：５１例手术患儿（年龄４２ｄ～８岁，体重４～２２ｋｇ），用“氯－芬”合剂微泵滴注行非插管全凭静脉麻醉，术中监测ＭＡＰ，ＨＲ，ＲＲ，ＳｐＯ２，定时查动脉血气。结果：术中镇痛完善，患儿安静，分泌物少，停药后１０～３０ｍｉｎ苏醒。术中ＭＡＰ、ＨＲ、ＲＲ、ＳｐＯ２、ｐＨ和ＰａＣＯ２无明显变化（Ｐ＞０．０５）；ＰａＯ２和ＳａＯ２于术中１５ｍｉｎ显著高于术前（Ｐ＜０．０５）。结论：“氯－芬”合剂微泵法可控性强，给药均匀且用量少，镇静镇痛完善，对呼吸、循环影响轻微，术毕苏醒快，无明显并发症。Objective:To study clinical effect of Ketamine fentanyl (K F) mixture microinstillation in pediatric intravenous anesthesia on the pediatric cardiopulmonary system.Methods:Fifty one pediatric patients were anesthesized intravenously with“K F” mixture microinstillation without endotracheal intubation,and MAP,HR,RR,SpO 2 etc were monitored continuously during operation Blood gas analysis was conducted in fixed time.Results:This method produced complete analgesia and stimulated little secretion.The pediatric patients recovered ten to thirty minutes after the adminstration of medicine.Compared with the level of preinduction,MAP,HR,RR,SpO 2,pH and PaCO 2 showed no significant change( P >0.05).PaO 2 and SaO 2 of 15 minutes during operation were significantly higher than preoperative level ( P <0.05).Conclusion:The study suggests that the method has strong controllability and small dosage with a stable plasma concentration and mild influence on the pediatric cardiopulmonary system,produces camplete analgesia and sedation,and rapid recovery without significant complication.

关 键 词：静脉麻醉 氯胺酮 芬太尼 儿童 全身麻醉 

分 类 号：R726.142.4[医药卫生—儿科]