每搏量变异度与患者血容量变化的相关性  

Correlation between stroke volume variation and blood volume

作　　者：王合梅[1] 贾慧群[1] 雍芳芳[1] 李超[1] 王勇[1] 赵伟[1] 

机构地区：[1]河北医科大学附属第四医院麻醉科,石家庄市050011

出　　处：《中华麻醉学杂志》2010年第7期814-816,共3页Chinese Journal of Anesthesiology

基　　金：基金项目：河北省普通高等学校强势特色学科肿瘤学建设经费资助项目;河北省科技厅指令性课题（07276101D-106）

摘　　要：目的评价每搏量变异度（SVV）与患者血容量变化的相关性。方法择期胃癌根治术男性患者48例，年龄50—60岁，ASA分级Ⅱ级。麻醉诱导后30min静脉输注6％羟乙基淀粉130／0．40．67ml·kg-1·min-1，分别于输注前、输注羟乙基淀粉剂量达2、4、6、8、10、12、14、16、18ml／kg时，记录SVV、CO、SV、CI和CVP。SVV、CO、SV、CI和CVP与羟乙基淀粉输注量行Spearman等级相关分析。结果SVV、CO、SV、CI和CVP与羟乙基淀粉输注量之间的相关系数分别为：rSVV=-0．91±0．06，rco=0．83±0．04，rsv=0．86±0．09，rcr=0．86±0．09，rcvp=0．90±0．03。5个相关系数中，rsvv最高，rcvp高于rco、rsv和rcl（P〈0．05）；rco、rsy和rcl间比较差异无统计学意义（P〉0．05）。结论SVV与患者血容量变化相关性较高，可用于指导容量治疗。Objective To evaluate the correlation between stroke volume variation （SVV） and the blood volume. Methods Forty-eight ASA II male patients, aged 50-60 yr, scheduled for elective radical operation for gastric cancer, were studied. Anesthesia was induced with fentanyl 4 ug/kg, propofol 2 mg/kg and cis-atracurium 0.15 mg/kg and maintained with inhalation of 2%-3% sevoflurane. 6% HES 130/0.4 was infused intravenously at a rate of 0.67 ml·kg-1·min-1 30 min after induction. SVV, cardiac output （CO）, SV and cardiac index （CI） were monitored and recorded using the FloTrae/Vigileo （Edwards Lifeseienees, USA） system before HES was infused and when the dose of HES reached 2, 4, 6, 8, 10, 12, 14, 16 and 18 ml/kg. CVP was also recorded at the corresponding time points. Spearman＇s rank sum correlation coefficient was used to analyze the data. Results Correlation coefficients between the amount of HES infused and CO, SV, CI or CVP were rsvv = - 0.91 ± 0.06, rco=0.83±0.04, rsv =0.86±0.09, rcl =0.86±0.09 and rcvp =0.90±0.03. Among the 5 correlation coefficients, rsvv was the highest, rcvp was significantly higher than rco, rsv and rcl（P〈 0.05）, and there was no significant difference among rco, rsv and rcl （ P 〉 0.05）. Conclusion SVV is highly correlated with the blood volume and can be used to guide volume therapy.

关 键 词：每搏输出量 血管容量 

分 类 号：R614[医药卫生—麻醉学]