探讨血清视黄醇结合蛋白的检测在肾脏疾病中的临床应用  

The discussion serum retinol-binding protein of the examination in the kidney disease′s clinical practice

作　　者：孟庆涛[1] 张瑜[1] 陈大力[1] 

机构地区：[1]山东省潍坊市益都中心医院检验科,山东青州262500

出　　处：《中国卫生检验杂志》2010年第11期2908-2908,2910,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的:探讨血清视黄醇结合蛋白(sRBP)在肾脏疾病中的临床意义。方法:选取本院78例肾脏疾病患者作为研究对象,并随即抽取同期健康者66名作为对照组,测定sRBP、尿视黄醇结合蛋白(uRBP)、尿素氮、肌酐、血β2-微球蛋白,并进行相关的统计学分析。结果:肾病患者的sRBP的结果(88.25±29.82),对照组(49.56±15.26),肾病组明显高于对照组(P<0.01)。结论:sRBP可以作为反映肾功能异常的较敏感指标,是评价肾病患者肾功能受损程度及部位的重要参数。Objective：To explore the value of Serum Retinol-binding Protein（sRBP,） in kidney disease.Methods： Selected 78 cases of hospital patients with kidney disease as a research object,and then extract the same period in66 healthy subjects as control group,measured sRBP,urinary retinol binding protein（uRBP）,urea nitrogen,creatinine,serum β2-microglobulin,and associated statistical analysis.Results： The nephrosis patient′s sRBP result：（88.25±29.82）,the control group（49.56±15.26）,the nephrosis group is higher than the control group obviously（P0.01）.Conclusion： sRBP may take the reflection kidney function unusual sensitive target,which is appraises the nephrosis patient kidney function damage degree and the part of the important parameters..

关 键 词：视黄醇结合蛋白 肾脏疾病 

分 类 号：Q513[生物学—生物化学]