体质指数与前列腺穿刺阳性率的关系探讨  

Relationship of body mass index with cancer detection in prostate biopsy

作　　者：陈海昕[1] 王翔[1] 张冠[1] 方自林[1] 丁振山[1] 刘乃波[1] 

机构地区：[1]卫生部中日友好医院泌尿外科,北京100029

出　　处：《中华医学杂志》2010年第40期2820-2822,共3页National Medical Journal of China

摘　　要：目的 探讨体质指数与前列腺穿刺阳性率的关系.方法 分析行前列腺穿刺活检患者168例,体质指数≥25为肥胖组,体质指数＜25为非肥胖组,比较两组间前列腺特异抗原（PSA）、前列腺体积、前列腺穿刺阳性率及病理结果.对所得数据进行统计学分析.结果 肥胖组前列腺穿刺阳性率为67.1%（51/76）,PSA：（25.2±33.7）μg/L;非肥胖组48.9%（45/92）,PSA：（40.9±43.3）μg/L,两组穿刺阳性率比较差异有统计学意义（P＜0.05）.可见肥胖组病例虽然PSA值偏低,但穿刺阳性率高于非肥胖组.Logistics回归分析,可见BMI≥25,是前列腺穿刺阳性预测的独立因素.结论 体质指数升高可增加前列腺穿刺阳性率.Objective To investigate the relationship of body mass index with cancer detection on prostate biopsy. Methods A total of 168 patients undergoing a prostate biopsy were divided into obese and non-obese groups by BMI ≥ 25 or 〈 25. Then the differences of prostate-specific antigen （PSA） level,prostate volume, prostate cancer detection rate and pathology result between two groups. Results The obese group had a higher rate of cancer detection than the non-obese group [67.1% （51/76） vs 48.9% （45/92）,P 〈 0.05 =. Logistics regression analysis showed that BMI ≥ 25 had a positive correlation with cancer detection on biopsy. Conclusion Body mass index can raise the risk of prostate cancer on biopsy.

关 键 词：前列腺肿瘤 体质指数 肥胖 前列腺穿刺 

分 类 号：R686[医药卫生—骨科学]