新疆南疆地区微量元素锂和碘与地方性甲状腺肿的关系  

The Relationship between the Trace Element Lithium and Endemic Goiter in Southern Area of Xinjiang

作　　者：刘勇[1] 陈祖培[2] 陈贯一[2] 项建梅[2] 阎玉芹[2] 杜小红[3] 朱惠民[4] 刘守军[5] 王荫谷 

机构地区：[1]天津医科大学总医院内分泌科,300052 [2]天津医科大学内分泌研究所 [3]中国人民解放军第二七二医院 [4]河北医科大学 [5]中国地方病防治研究中心 [6]阿克苏地办室

出　　处：《天津医药》1999年第5期262-263,共2页Tianjin Medical Journal

基　　金：国家自然科学基金

摘　　要：目的：研究碘缺乏病流行地区除严重缺碘外，微量元素提对甲状腺肿的影响。方法：对新疆拜城县的两个乡进行流行病学调查，测定当地外环境碘含量，对当地的饮水和妇女的血清锂用原子吸收光谱法进行测定。结果：该地区外环境明显碘缺乏，饮水、土盐、土壤和粮食碘含量均低于国家标准。当地为甲状腺肿的高发重度病区，当地饮水和居民血清锂含量均显著高于对照组。结论：除缺碘外，高锂可能是造成碘缺乏病流行的另一种致甲状腺肿物质。Objective: To investigate the effect of trace element lithium on the occurrence of endemic gaiter. Methods: An epidemi- ological investigation was carried out in two townships of Baicheng county in Xinjiang. The iodine content in the local envir- onment was measured. Meanwhile, atomic absorbance spetrophotometer was employed to measure the lithium content in the local drinking water and female serum. Results:The apparent deficiency of iodine was detected in the environment with high incidence of endemic goiter. The lithium content in the local drinking water and the resident's serum was significantly higher than that in normal people in Tianjin. Conclusion: It was indicated that high lithium may be another goitrogenic factor mak- ing iodine-deficiency disease locally epidemic.

关 键 词：甲状腺肿 地方性 微量元素 锂 碘 

分 类 号：R581.302[医药卫生—内分泌]