BiPAP治疗COPD合并Ⅱ型呼吸衰竭疗效观察  

Clinic Therapeutic Effect of Using Bilevel Positive Airway Pressure Non-invasive Ventilator on Chronic Obstructive Pulmonary Disease and Respiratory Failure

作　　者：孙军[1] 帅雪芬 陈学东[1] 

机构地区：[1]安徽省宣城市人民医院呼吸内科,242000

出　　处：《中华全科医学》2010年第12期1537-1538,共2页Chinese Journal of General Practice

摘　　要：目的探讨双水平气道正压无创通气(BiPAP)对慢性阻塞性肺疾病(Chronic Obstructive Pulmonary Disease,COPD)合并Ⅱ型呼吸衰竭的治疗价值。方法将46例COPD合并Ⅱ型呼衰患者分成通气组和对照组,对照组给予常规抗感染、解痉平喘、激素、吸氧等综合治疗,通气组除了常规治疗外,还给予无创机械通气(BiPAP)治疗,两组分别在治疗前、治疗4h和24h作血气分析检查,并对两组的pH值、SaO2、PaO2、PaCO2的变化,以及临床症状改善情况做一比较。结果 46例患者均能配合治疗,取得了较为满意的临床疗效。通气组治疗后患者的症状和体征以及血气分析中pH值、SaO2、PaO2、PaCO2较治疗前均明显改善,其改善幅度明显优于对照组。结论双水平气道正压无创通气治疗COPD合并Ⅱ型呼吸衰竭疗效显著。因此,对于临床稳定、仍需长期机械通气的呼吸衰竭患者,使用BiPAP无创呼吸机通气是可选择的方法。Objective To study the clinic therapeutic effect of using bilevel positive airway pressure non-invasive ventilator on chronic obstructive pulmonary disease and respiratory failure. Methods The total of 46 patients with chronic obstructive pulmonary disease and respiratory failure were divided into experimental group （23 cases） and control group （23 cases）. The routine therapy was given in the two groups, but noninvastive ventilation and the routine therapy both were given in the experimental group. The blood gas analysis was evaluated after 4 h and 24 h, the changes of Artery pH, SaO2, PaO2, PaCO2 and clinical symptoms were compared between the two groups. Results The clinical effect of treatment in patients was very satisfactory with this treatment under the cooperation of patients. After the treatment, the arterial blood gas and physical sign of experimental group was apparently im- proved than control group. Conclusion Bilevel positive airway pressure non-invasive ventilator can improve the therapeutic effect of the patients with chronic obstructivepulmonary disease and respiratory failure. The method was an alternative choice for stable patients needing prolonged mechanical ventilation.

关 键 词：无创机械通气 慢性阻塞性肺疾病(COPD) II型呼吸衰竭 

分 类 号：R563.805[医药卫生—呼吸系统]