儿童变应性鼻炎T细胞亚群检测分析  

Analysis of T cell subgroup in children with allergic rhinitis

作　　者：李怡[1] 李乃麟[1] 潘春莹[2] 

机构地区：[1]天津市儿童医院耳鼻咽喉科,天津300074 [2]天津市儿童医院儿研所

出　　处：《临床耳鼻咽喉科杂志》1999年第5期206-207,共2页Journal of Clinical Otorhinolaryngology

摘　　要：观察正常儿童与变应性鼻炎患儿外周血Ｔ细胞亚群分布的差异。方法：用间接免疫荧光法随机检测儿童变应性鼻炎组１６例和正常对照组２０例，并进行统计学分析。结果：变应性鼻炎组外周血中ＣＤ３、ＣＤ４、ＣＤ８较对照组均有明显下降。结论：Ｔ细胞亚群分布的改变是变态反应性疾病免疫功能紊乱的重要环节，可以作为变应性疾病的监测指标。Objective :To observe the different distribution of T cell in peripheral blood between normal children and children with allergic rhinitis. Method: We use the indirect immunoflurorescence to make a statisticalanalysis randomly in 16 children with allergic rhinitis and 20 in control group. Result:CD3,CD4,CD8in peripheralblood of patients are a lot less than those in normal children. Conclusion :The change of T cell subgroup'S distribution is an important process of immune mechanism disturbance and can be used as a monitoring standard in allergic diseases.

关 键 词：儿童 变应性鼻炎 T细胞亚群 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]